Cherryman G R, Smith F W
Clin Radiol. 1985 Sep;36(5):539-40. doi: 10.1016/s0009-9260(85)80216-6.
The nuclear magnetic resonance images obtained in a case of adrenoleukodystrophy are presented. The areas of demyelination are clearly seen. The T1 values of the affected areas are not specific and coincide with those previously recorded in the lesions of multiple sclerosis or cerebrovascular disease. A diagnosis of adrenoleukodystrophy should be considered in younger male patients presenting with behavioural disturbances, especially when these are associated with abnormalities of vision or gait. There may be no clinical evidence of the associated adrenocortical insufficiency.
本文展示了一例肾上腺脑白质营养不良患者的核磁共振成像。脱髓鞘区域清晰可见。受累区域的T1值并无特异性,与先前在多发性硬化症或脑血管疾病病变中记录的值一致。对于出现行为障碍的年轻男性患者,尤其是当这些行为障碍与视力或步态异常相关时,应考虑肾上腺脑白质营养不良的诊断。可能没有相关肾上腺皮质功能不全的临床证据。