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腮腺上皮-肌上皮癌,9年后发生淋巴结转移:1例病例报告

Parotid Epithelial-Myoepithelial Carcinoma, Lymph Node Metastasis After 9 Years: A Case Report.

作者信息

Bianco Maria Rita, Galletti Cosimo, Maniaci Antonino, Torrice Giovanni, Allegra Eugenia

机构信息

Otolaryngology, Department of Health Science, University of Catanzaro, 88100 Catanzaro, Italy.

Otolaryngology, Department of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.

出版信息

Reports (MDPI). 2024 Nov 15;7(4):99. doi: 10.3390/reports7040099.

Abstract

: Epithelial-myoepithelial carcinoma (EMC) is a rare, low-grade malignant tumor of the salivary glands. It is characterized by a low malignancy potential, as indicated by its low rate of lymph node involvement and distant metastasis, and has a local recurrence rate of approximately 50%. Due to the rarity of EMC and the limited data available in the literature, there are no established treatment or follow-up guidelines. : We report the case of an 83-year-old man who presented with swelling in the left submandibular region, occurring 9 years following an initial diagnosis of EMC in the ipsilateral parotid gland. After radiological examinations and an ultrasound-guided fine-needle aspiration biopsy, the patient underwent surgical excision of the lesion with a histological diagnosis of recurrence/metastasis of low-grade epithelial-myoepithelial carcinoma. : This is the first documented case of loco-regional lymph node metastasis 9 years after an initial diagnosis of EMC of the parotid gland. Based on our experience, EMC of the parotid gland, even when diagnosed at an early stage, seems to require a long follow-up period.

摘要

上皮-肌上皮癌(EMC)是一种罕见的涎腺低度恶性肿瘤。其特点是恶性潜能低,淋巴结受累率和远处转移率低,局部复发率约为50%。由于EMC罕见且文献中的数据有限,目前尚无既定的治疗或随访指南。

我们报告了一例83岁男性患者,其在同侧腮腺初次诊断为EMC 9年后出现左下颌下区肿胀。经过影像学检查和超声引导下细针穿刺活检,患者接受了病变的手术切除,组织学诊断为低度上皮-肌上皮癌复发/转移。

这是腮腺EMC初次诊断9年后发生局部区域淋巴结转移的首例文献记载病例。根据我们的经验,腮腺EMC即使在早期诊断,似乎也需要较长的随访期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e83/12199925/2301bdbd682a/reports-07-00099-g001.jpg

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