Nie Jiaqian, Zhao Jiantian, Li Lina, Zhou Tianyi, Guerin Gerald
Shanghai Key Laboratory of Advanced Polymeric Materials, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China.
Angew Chem Int Ed Engl. 2025 Aug 4:e202511515. doi: 10.1002/anie.202511515.
All the objects that surround us can be seen as combinations of elementary shapes like spheres, rods, and squares that perform complex tasks when connected in a well-defined manner. While making a device by assembling those shapes remains relatively easy at the human scale, it is extremely challenging to do so at the nanoscale, due to the difficulty to covalently attach at a defined position a nano-object with a given shape to another one of different geometry. To circumvent this hurdle, here, we introduce an innovative approach that consists in performing polymerization-induced self-assembly (PISA) onto core-crystalline micelles prepared by crystallization-driven self-assembly (CDSA). Because of the intrinsic properties of CDSA, one can construct one- or two-dimensional substrates to initiate PISA at very specific locations. Performing CDSA-substrated-PISA (CDSA-s-PISA) onto triblock co-micelles where only the central block was PISA active, led to the formation of elongated structures bearing one or two beads on their central parts, while CDSA-s-PISA on entirely PISA active micelles and in presence of free macro-CTA, allowed the preparation of uniform elongated micelles fully decorated with beads. These results offer a sneak peek of what the next generation of multitasks polymeric assemblies will be.
我们周围的所有物体都可以看作是由球体、棒体和方形等基本形状组合而成，这些形状以明确的方式连接时可执行复杂任务。虽然在人类尺度上通过组装这些形状制造设备相对容易，但在纳米尺度上却极具挑战性，因为很难将具有给定形状的纳米物体在特定位置共价连接到另一个不同几何形状的物体上。为了克服这一障碍，在此我们引入一种创新方法，即对通过结晶驱动自组装（CDSA）制备的核晶态胶束进行聚合诱导自组装（PISA）。由于CDSA的固有特性，可以构建一维或二维底物，在非常特定的位置引发PISA。在仅中间嵌段具有PISA活性的三嵌段共胶束上进行CDSA底物介导的PISA（CDSA-s-PISA），会导致在其中心部分形成带有一个或两个珠子的细长结构，而在完全具有PISA活性的胶束上且存在游离大分子CTA的情况下进行CDSA-s-PISA，则可以制备出完全用珠子装饰的均匀细长胶束。这些结果让我们初步了解了下一代多任务聚合物组装体将会是什么样。
