Xu Fei, Zhou Siyu, Wang Ben, Sun Zhuoran, Jiang Shuai, Li Zhuofu, Li Weishi
Orthopaedic Department, Peking University Third Hospital, Beijing, China.
Orthopaedics Department, Beijing Key Laboratory of Spinal Disease Reasearch, Beijing, China.
Global Spine J. 2025 Aug 4:21925682251362138. doi: 10.1177/21925682251362138.
Study DesignRetrospective study.ObjectiveThis study aims to identify how CT HU values vary in degenerative lumbar scoliosis (DLS) patients with different scoliotic apexes and in those with different degree of scoliosis.MethodsWe included 222 DLS patients and 140 lumbar spinal stenosis (LSS) patients, dividing the DLS patients into 2 groups based on scoliotic apex location. Patients were further categorized by T scores into osteoporotic and non-osteoporotic groups, and by Cobb angle into mild (<20°) and severe (>20°) scoliosis. We analyzed CT value distribution in these groups and compared the area under the curve (AUC) for predicting osteoporosis based on HU values from different vertebrae.ResultsCT HU values for L1 and L2 were significantly lower in the DLS group compared to LSS group ( < 0.05). The lowest HU values in patients with a scoliotic apex at L2 or L2-3 were observed at the scoliotic apex region, while those with the scoliotic apex at L3, L3-4, and L4 had the lowest values at L3. This pattern was more pronounced in patients with a Cobb angle >20°. In the mild scoliosis group, the lowest CT value was found at L3 when the scoliotic apex was between L2 and L4. Additionally, L4 CT HU thresholds were better at distinguishing osteoporosis than other levels ( < 0.05), swhen the scoliotic apex was located at L2 or L2-3.ConclusionsCT HU values in DLS patients, particularly with a Cobb angle >20°, decrease at the scoliotic apex. Caution is required when using HU values from L1, L2, and L3 to assess osteoporosis in patients with a scoliotic apex at L2 and L2-3.
研究设计
回顾性研究。
目的
本研究旨在确定不同脊柱侧凸顶点的退行性腰椎侧凸(DLS)患者以及不同脊柱侧凸程度的患者中CT HU值如何变化。
方法
我们纳入了222例DLS患者和140例腰椎管狭窄症(LSS)患者,根据脊柱侧凸顶点位置将DLS患者分为2组。患者进一步按T值分为骨质疏松组和非骨质疏松组,并按Cobb角分为轻度(<20°)和重度(>20°)脊柱侧凸。我们分析了这些组中的CT值分布,并比较了基于不同椎体HU值预测骨质疏松症的曲线下面积(AUC)。
结果
与LSS组相比,DLS组L1和L2的CT HU值显著更低(<0.05)。脊柱侧凸顶点位于L2或L2 - 3的患者,在脊柱侧凸顶点区域观察到最低的HU值,而脊柱侧凸顶点位于L3、L3 - 4和L4的患者在L3处HU值最低。这种模式在Cobb角>20°的患者中更明显。在轻度脊柱侧凸组中,当脊柱侧凸顶点位于L2和L4之间时,最低CT值在L3处发现。此外,当脊柱侧凸顶点位于L2或L2 - 3时,L4的CT HU阈值在区分骨质疏松症方面比其他水平更好(<0.05)。
结论
DLS患者的CT HU值,特别是Cobb角>20°的患者,在脊柱侧凸顶点处降低。当使用L1、L2和L3的HU值评估脊柱侧凸顶点位于L2和L2 - 3的患者的骨质疏松症时需要谨慎。