Bradfield J Y, Locke J, Wyatt G R
DNA. 1985 Oct;4(5):357-63. doi: 10.1089/dna.1985.4.357.
The genome of the African migratory locust, Locusta migratoria (Class Insecta, Order Orthoptera, Family Acrididae) contains an interspersed DNA sequence family, designated the Lm1 family. This family consists of short (approximately 195-bp), widely dispersed, highly reiterated (approximately 6 X 10(5) copies/haploid genome) repeat units, which account for about 2% of the locust genome. Lm1 repeats contain regions that closely resemble internal promoter sequences for RNA polymerase III, and they are structurally very similar to RNA polymerase III templates. Family members are flanked by short direct repeats, and are closely linked to structural genes. These features are reminiscent of the Alu family of man and other repeat sequence families, until now documented only in higher vertebrates.
非洲迁徙蝗虫(Locusta migratoria,昆虫纲,直翅目,蝗科)的基因组包含一个散布的DNA序列家族,命名为Lm1家族。这个家族由短的(约195碱基对)、广泛分布、高度重复(约6×10⁵个拷贝/单倍体基因组)的重复单元组成,约占蝗虫基因组的2%。Lm1重复序列包含与RNA聚合酶III内部启动子序列非常相似的区域,并且在结构上与RNA聚合酶III模板非常相似。家族成员两侧有短的直接重复序列,并且与结构基因紧密相连。这些特征使人联想到人类的Alu家族和其他重复序列家族,直到现在这些家族仅在高等脊椎动物中被记录到。