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欧洲喉科学会关于早期声门癌治疗后最佳监测方案的共识声明:风险分层

European Laryngological Society consensus statement on optimal monitoring schedules after treatment for early glottic cancer: a risk-stratification.

作者信息

Wierzbicka Malgorzata, Baidun Agatha, Bertolin Andy, Lionello Marco, Succo Giovanni, Verbist Berit, Farina Davide, Hendriksma Martine, Remacle Marc, Simo Ricard, Sjogren Elisabeth, Piazza Cesare

机构信息

Faculty of Medicine, Wroclaw University of Science and Technology, 27 Wybrzeże Stanisława Wyspiańskiego st, Wrocław, 50-370, Poland.

Institute of Human Genetics Polish Academy of Sciences, 32 Strzeszyńska st., Poznań, 60-479, Poland.

出版信息

Eur Arch Otorhinolaryngol. 2025 Sep;282(9):4699-4710. doi: 10.1007/s00405-025-09609-0. Epub 2025 Aug 4.

Abstract

Early glottic cancer has an excellent prognosis provided that recurrences are detected in a timely manner. However, current guidelines lack specific recommendations for intervals or interventions during follow-up, and primarily advocate surveillance in the most advanced stages where the benefits are actually the lowest. This consensus statement introduces a risk-stratification-guided follow-up schedule for T1-T2N0 patients, aiming to optimize oncologic and functional outcomes while ensuring early detection of residual or recurrent disease to preserve organ function. Separate protocols are outlined for surgical and non-surgical patients, including endoscopic examination, radiological imaging, and thyroid function screening. Also, the pathway to reach this routine observation phase is described, specifying the criteria and timing of a second-look microlaryngoscopy.

摘要

早期声门癌若能及时发现复发,预后极佳。然而,当前指南缺乏关于随访期间检查间隔或干预措施的具体建议,主要主张在受益实际上最低的最晚期阶段进行监测。本共识声明为T1-T2N0患者引入了基于风险分层的随访计划,旨在优化肿瘤学和功能结局,同时确保早期发现残留或复发性疾病以保留器官功能。针对手术和非手术患者制定了单独的方案,包括内镜检查、影像学检查和甲状腺功能筛查。此外,还描述了进入这一常规观察阶段的途径,明确了二次显微喉镜检查的标准和时机。

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