Segrin Chris, Badger Terry A, Cunicelli Nathan, Sikorskii Alla
Department of Communication, University of Arizona, Tucson, Arizona, USA.
Advanced Nursing Practice and Science Division, University of Arizona College of Nursing, Tucson, Arizona, USA.
Psychooncology. 2025 Aug;34(8):e70250. doi: 10.1002/pon.70250.
Cancer survivors and their caregivers can experience interdependent symptoms.
The objective of this research was to determine if participation in a telephone delivered interpersonal counseling intervention, compared to an educational intervention, increases observed dyadic interdependence in depression, anxiety, and other symptoms in cancer survivors and their informal caregivers.
A dyadic sample of survivors in treatment for solid tumor cancers and their caregivers participated in a 17-week sequential multiple assignment trial of symptom management interventions. Participants completed weekly measures of depression, anxiety, and other symptoms. Initially, all survivors and caregivers received a Symptom Management and Survivorship Handbook (SMSH) intervention. Survivors who still had unresolved depression or anxiety symptoms after 4 weeks were randomized with their caregivers to continue with SMSH alone or add a telephone interpersonal counseling (TIPC) intervention for the next 8 weeks (N = 87). For this sample, the lagged-dependent Actor-Partner Interdependence Model was used to estimate longitudinal actor and partner effects for each of the three symptom measures. Interaction terms representing intervention condition (SMSH vs. SMSH + TIPC) were entered into the models to determine if intervention moderated the observed actor or partner effects.
The caregiver→survivor partner effect for anxiety was significantly stronger in the SMSH + TIP arm compared to the SMSH alone arm. No other moderation effects were observed.
Participating in the interpersonal counseling intervention as an addition to an educational intervention delivered to both members of a survivor-caregiver dyad does not appear to affect dyadic interdependence in symptoms other than anxiety.
癌症幸存者及其照料者可能会出现相互依存的症状。
本研究的目的是确定与教育干预相比，参与电话人际咨询干预是否会增加癌症幸存者及其非正式照料者在抑郁、焦虑和其他症状方面观察到的二元相互依存性。
对正在接受实体肿瘤癌症治疗的幸存者及其照料者组成的二元样本进行了一项为期17周的症状管理干预序贯多重分配试验。参与者每周完成抑郁、焦虑和其他症状的测量。最初，所有幸存者和照料者都接受了症状管理与生存手册（SMSH）干预。4周后仍有未解决的抑郁或焦虑症状的幸存者与其照料者被随机分组，继续单独接受SMSH干预或在接下来的8周内增加电话人际咨询（TIPC）干预（N = 87）。对于该样本，使用滞后依存性的行为者-伙伴相互依存模型来估计三种症状测量中每种测量的纵向行为者和伙伴效应。将代表干预条件（SMSH与SMSH + TIPC）的交互项纳入模型，以确定干预是否调节了观察到的行为者或伙伴效应。
与单独接受SMSH干预的组相比，接受SMSH + TIP干预的组中照料者对幸存者的焦虑伙伴效应显著更强。未观察到其他调节效应。
作为对幸存者-照料者二元组双方进行的教育干预的补充，参与人际咨询干预似乎不会影响除焦虑以外的症状的二元相互依存性。
