Miller P J, Holmes J R
Equine Vet J. 1985 May;17(3):181-90. doi: 10.1111/j.2042-3306.1985.tb02465.x.
Observations on seven cases of mitral insufficiency are described. Three of the horses had recent histories of cardiac failure and formed a separate group in which there were marked haemodynamic changes which varied in relation to heart rate but were associated with pulmonary hypertension, elevated right ventricular pressure and low peak left ventricular pressure. In the other four horses the heart appeared to be compensating at rest but to be unable to cope with severe exertion. On auscultation, a widespread pansystolic murmur and a prominent third heart sound were characteristic of the left ventricular volume overload. Microscopic changes were found in one left papillary muscle. The possibility that changes in the position of the papillary muscles consequent upon left ventricular dilatation may lead to or exaggerate mitral valve eversion is discussed.
描述了对7例二尖瓣关闭不全病例的观察结果。其中3匹马近期有心力衰竭病史，形成一个单独的组，该组存在明显的血流动力学变化，这些变化随心率而变化，但与肺动脉高压、右心室压力升高和左心室压力峰值降低有关。另外4匹马在休息时心脏似乎处于代偿状态，但无法应对剧烈运动。听诊时，广泛的全收缩期杂音和明显的第三心音是左心室容量超负荷的特征。在一块左乳头肌中发现了微观变化。讨论了左心室扩张导致乳头肌位置改变可能导致或加剧二尖瓣翻转的可能性。
