Regnouf F, Nguyen E, Cassoly R, Pradel L A
Eur J Biochem. 1985 Dec 2;153(2):313-9. doi: 10.1111/j.1432-1033.1985.tb09303.x.
Thyroid spectrin has been obtained pure from pig thyroid glands. This protein, composed of two non-identical polypeptide chains of 240 kDa and 235 kDa, appears to possess the same structural and immunological properties as well as the same calmodulin and actin-binding properties as brain spectrin. Through cross-linking of actin filaments it is a potent gelation factor for F-actin solutions. It represents one of the major protein of the cytoskeleton underlying the thyroid plasma membrane together with myosin, alpha-actinin and actin.
甲状腺血影蛋白已从猪甲状腺中提纯获得。这种蛋白质由两条分子量分别为240 kDa和235 kDa的不同多肽链组成，似乎具有与脑血影蛋白相同的结构和免疫特性，以及相同的钙调蛋白和肌动蛋白结合特性。通过肌动蛋白丝的交联，它是F-肌动蛋白溶液的一种强效凝胶化因子。它与肌球蛋白、α-辅肌动蛋白和肌动蛋白一起，是甲状腺质膜下细胞骨架的主要蛋白质之一。
