Zhang S X, Yang Z, Tang H, Wang S L, Chen Y, Zhang Y H
Department of Pulmonary and Critical Care Medicine, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China.
Department of Pathology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2025 Aug 12;48(8):744-747. doi: 10.3760/cma.j.cn112147-20250418-00213.
Invasive (ITBA) is a relatively rare manifestation of invasive pulmonary aspergillosis(IPA), which usually occurrs in immunocompromised patients and with a fatal outcome. Here, we reported a 37-year-old immunocompetent male patient with psoriasis who was hospitalized for dyspnea. Bronchoscopy revealed pseudomembranous tracheobronchitis, and ITBA was subsequently confirmed pathologically. Despite receiving standardized antifungal therapy with voriconazole, the patient developed to severe airway stenosis. For ITBA, follow-up with bronchoscopy was necessary to exclude tracheal stenosis.
侵袭性气管支气管曲霉病（ITBA）是侵袭性肺曲霉病（IPA）相对罕见的一种表现形式，通常发生在免疫功能低下的患者中，且预后不良。在此，我们报告了一名37岁患有银屑病的免疫功能正常男性患者，因呼吸困难入院。支气管镜检查显示为假膜性气管支气管炎，随后经病理证实为ITBA。尽管接受了伏立康唑标准化抗真菌治疗，但患者仍发展为严重气道狭窄。对于ITBA，有必要通过支气管镜检查进行随访以排除气管狭窄。
