Loumaye E, Donnez J, Thomas K
Fertil Steril. 1985 Dec;44(6):827-9. doi: 10.1016/s0015-0282(16)49045-x.
Concentrations of P and E2 were measured in serum and PF obtained from 34 laparoscopies performed in 18 patients for oocyte retrieval in an in vitro fertilization program. Samples from group A (28 patients who had not ovulated at laparoscopy) and group B (6 patients who had ovulated very shortly before laparoscopy) were compared. No difference was observed in serum steroid levels between the two groups; however, group B showed a 100-times increase in E2 concentration and a 200-times increase in P concentration measured in the PF. In conclusion, we can postulate that this sudden and large increase in PF steroids after ovulation is initially solely dependent on the mechanic rupture of the follicle and not on its luteinization.
在一项体外受精计划中，对18例接受腹腔镜取卵手术的患者进行了34次腹腔镜检查，测定了血清和卵泡液中P（孕酮）和E2（雌二醇）的浓度。比较了A组（28例腹腔镜检查时未排卵的患者）和B组（6例腹腔镜检查前不久排卵的患者）的样本。两组血清类固醇水平未见差异；然而，B组卵泡液中测得的E2浓度增加了100倍，P浓度增加了200倍。总之，我们可以推测，排卵后卵泡液中类固醇的这种突然大幅增加最初仅取决于卵泡的机械性破裂，而非其黄素化。
