Abera Asmamaw, Aseffa Abraham, Mengistie Bezatu, Malmqvist Ebba, Isaxon Christina, Sahilu Geremew
Ethiopia Institute of Water Resources, Addis Ababa University, 150461, Addis Ababa, Ethiopia.
Armauer Hansen Research Institute, 1005, Addis Ababa, Ethiopia.
Sci Rep. 2025 Aug 5;15(1):28571. doi: 10.1038/s41598-025-13821-7.
Fluoride toxicity has become a significant global public health concern, with drinking water being a major source of exposure. This study aimed to determine groundwater fluoride concentration and assess its non-carcinogenic health effects on human health. A longitudinal study design was applied to select water samples in dry and wet seasons from Adama City and Wenji Gefersa town of Ethiopia. Groundwater fluoride concentration was measured using an ion-selective electrode. Total hazard analysis was assessed based on the chronic daily oral intake and dermal absorbed dose of fluoride. Analyses were conducted using ArcGIS, an Excel spreadsheet and Statistical Packages for the Social Sciences (SPSS). This study reported that groundwater fluoride concentration ranged from 0.3 mg/L to 38 mg/L, with the mean annual concentrations of Adama City and Wenji Gefersa Town being 1.9 mg/L and 23 mg/L, respectively. Fluoride concentrations reported at 70% and 45% of groundwater samples during the wet season and dry season were above World Health Organization (WHO) guidelines for drinking water. Total hazard index values among sampled locations varied from 0.17 to 30.43. Three-fourths of infants, 99% of children, 62% of adolescents, and 45% of adults had a risk of developing a non-carcinogenic health effect. This study demonstrated fluoride contamination of groundwater sources pose the residents for higher probability of developing non-carcinogenic health effects on their lifetimes. Application of locally available defluorination technology is paramount to safeguard the community.
氟中毒已成为一个重大的全球公共卫生问题,饮用水是主要的接触源。本研究旨在测定地下水中的氟浓度,并评估其对人体健康的非致癌健康影响。采用纵向研究设计,从埃塞俄比亚的阿达马市和温吉盖费尔萨镇在旱季和雨季采集水样。使用离子选择性电极测量地下水中的氟浓度。基于氟的慢性每日口服摄入量和皮肤吸收剂量进行总危害分析。使用ArcGIS、Excel电子表格和社会科学统计软件包(SPSS)进行分析。本研究报告称,地下水中的氟浓度范围为0.3毫克/升至38毫克/升,阿达马市和温吉盖费尔萨镇的年均浓度分别为1.9毫克/升和23毫克/升。在雨季和旱季,分别有70%和45%的地下水样本的氟浓度高于世界卫生组织(WHO)的饮用水指南。采样地点的总危害指数值在0.17至30.43之间。四分之三的婴儿、99%的儿童、62%的青少年和45%的成年人有产生非致癌健康影响的风险。本研究表明,地下水源的氟污染使居民在其一生中产生非致癌健康影响的可能性更高。应用当地可用的除氟技术对于保护社区至关重要。