Mohammed Jemal, Sium Abraham Fessehaye, Gudu Wondimu
Department of Obstetrics and Gynaecology, St. Paul's Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia.
Int J Gynaecol Obstet. 2025 Aug 6. doi: 10.1002/ijgo.70452.
To determine the live birth and preterm birth outcomes of pregnant women who conceived through assisted reproductive technology (ART) at a public in vitro fertilization (IVF) center in Ethiopia.
This descriptive study on pregnancy outcomes of women who conceived through ART (IVF and embryo transfer, IVF/intracytoplasmic sperm injection, and intrauterine insemination) was conducted at St. Paul's Hospital Millennium Medical College, in Ethiopia. We retrospectively analyzed the live birth rate, preterm birth rate, and other perinatal and maternal outcomes of women who conceived after ART at a public IVF center during 4 years (between 2019 and 2023) in St. Paul's Hospital. Patients who had IVF at this center between 2018 and 2020 were included in the study. Data were collected retrospectively in a structured questionnaire and analyzed and simple descriptive statistics were employed. Frequency and percentage were used to present the results.
From the 127 women included in the final analysis, the majority (101 of 127, 79.5%) were aged 35 years and younger, followed by another 21.3% (27 of 127) who were in the age category 36-40 years. The live birth rate was 93.7% (119 of 127). The preterm birth (<37 weeks of gestation) rate was 15.7% (20 of 127) but the majority (18 of 20, 90%) were at a gestational age ≥34 weeks, with only two (1.6%) patients having preterm birth at <34 weeks. Pre-eclampsia occurred in 12 women, constituting 9.45% of patients.
The live birth rate of 93.7% observed in this study is high and comparable to rates reported in high-income countries. However, the incidence of perinatal complications remains elevated. These findings can be used to inform couple counseling and support performance improvement initiatives at the fertility center.
确定在埃塞俄比亚一家公立体外受精（IVF）中心通过辅助生殖技术（ART）受孕的孕妇的活产和早产结局。
这项关于通过ART（IVF与胚胎移植、IVF/卵胞浆内单精子注射以及宫腔内人工授精）受孕女性妊娠结局的描述性研究在埃塞俄比亚的圣保罗医院千禧医学院开展。我们回顾性分析了圣保罗医院在4年（2019年至2023年）期间于一家公立IVF中心通过ART受孕女性的活产率、早产率以及其他围产期和孕产妇结局。纳入研究的患者为2018年至2020年期间在该中心接受IVF的患者。通过结构化问卷回顾性收集数据，并进行分析，采用简单描述性统计方法。结果以频率和百分比呈现。
在纳入最终分析的127名女性中，大多数（127名中的101名，79.5%）年龄在35岁及以下，其次是21.3%（127名中的27名）年龄在36 - 40岁。活产率为93.7%（127名中的119名）。早产（妊娠<37周）率为15.7%（127名中的20名），但大多数（20名中的18名，90%）孕周≥34周，只有两名（1.6%）患者在<34周早产。12名女性发生子痫前期，占患者的9.45%。
本研究观察到的93.7%的活产率较高，与高收入国家报告的比率相当。然而，围产期并发症的发生率仍然较高。这些发现可用于为夫妇咨询提供信息，并支持生育中心的绩效改进举措。
