Levy Jerrold H, Alexander Peta M A, Wolberg Alisa S, McCarty Owen J T, Pusateri Anthony E, Bartz Raquel R, Bergmeier Wolfgang, Cohen Mitchell J, Connors Jean M, Morrissey James H, Neal Matthew D, Tracy Elisabeth T, McCrae Keith, Sullenger Bruce A
Department of Anesthesiology, Critical Care, and Surgery (Cardiothoracic), Duke University School of Medicine, Durham, NC.
Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA.
Blood Vessel Thromb Hemost. 2025 Feb 25;2(2):100064. doi: 10.1016/j.bvth.2025.100064. eCollection 2025 May.
In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on "Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice." The event brought together clinicians, scientists, bioengineers, and policymakers to address the challenges of ECMO-associated coagulopathy and explore novel therapeutic approaches. Through expert presentations and collaborative discussions, the workshop focused on innovative anticoagulation strategies, precision medicine, and advanced diagnostics to enhance patient care. The discussions also identified critical research gaps and opportunities for future interdisciplinary collaboration. This summary reviews the current state of knowledge and outlines future research directions for improving ECMO-induced coagulopathy management.
2024年5月,美国国立心肺血液研究所(NHLBI)血液疾病与资源司主办了一场关于“体外膜肺氧合(ECMO)诱导的凝血病:研究与临床实践的战略举措”的混合研讨会。该活动汇聚了临床医生、科学家、生物工程师和政策制定者,以应对ECMO相关凝血病的挑战,并探索新的治疗方法。通过专家演讲和合作讨论,研讨会聚焦于创新的抗凝策略、精准医学和先进诊断,以改善患者护理。讨论还确定了关键的研究差距以及未来跨学科合作的机会。本总结回顾了当前的知识状况,并概述了改善ECMO诱导的凝血病管理的未来研究方向。