Grassi Alberto, Borque Kyle, Dietvorst Martijn, Altovino Emanuele, Rossi Claudio, Ambrosini Luca, Bondi Alice, Zaffagnini Stefano
Dipartimento di Scienze Biomediche e Neuromotorie DIBINEM Università di Bologna Bologna Italy.
Clinica Ortopedica e Traumatologica II, Istituto Ortopedico Rizzoli Bologna Italy.
J Exp Orthop. 2025 Aug 5;12(3):e70280. doi: 10.1002/jeo2.70280. eCollection 2025 Jul.
This study aimed to develop and validate a clinical decision-making algorithm, the 'Best ACL-treatment Based on the Years of the Knee' (BABY-Knee) Algorithm, for treating acute anterior cruciate ligament (ACL) injuries in skeletally immature patients. The algorithm integrates magnetic resonance imaging (MRI) findings and patient-specific characteristics to differentiate cases suitable for conservative management from those requiring surgical intervention.
A prospective cohort of 75 skeletally immature patients (mean age: 13.9 ± 2.2 years) diagnosed with ACL rupture at a single institution between February 2022 and October 2024 was evaluated. Patients were categorized as surgical or non-surgical candidates based on the BABY-Knee Algorithm, which incorporates six weighted criteria: MRI-detected meniscal tears, lateral tibiofemoral bone bruises, skeletal age, injury mechanism and rotatory laxity. Outcomes of initial management were retrospectively analyzed for algorithm validation.
Of the 75 patients, 55 (73.3%) underwent surgical reconstruction, while 20 (26.7%) were managed conservatively. Conservative treatment failed in 12 cases (60%), necessitating surgical intervention. Retrospective application of the algorithm yielded a positive predictive value of 91.7% for identifying surgical candidates and a negative predictive value of 87.5% for successful conservative treatment.
The BABY-Knee Algorithm demonstrated high reliability in guiding treatment decisions for skeletally immature patients with acute ACL injuries, predicting outcomes of conservative treatment in nearly 90% of cases. Further studies are required to confirm its applicability in additional prospective case series.
Level IV, case series.
本研究旨在开发并验证一种临床决策算法,即“基于膝关节年龄的最佳前交叉韧带治疗”(BABY-Knee)算法,用于治疗骨骼未成熟患者的急性前交叉韧带(ACL)损伤。该算法整合了磁共振成像(MRI)结果和患者特定特征,以区分适合保守治疗的病例与需要手术干预的病例。
对2022年2月至2024年10月期间在单一机构诊断为ACL断裂的75例骨骼未成熟患者(平均年龄:13.9±2.2岁)进行前瞻性队列研究。根据BABY-Knee算法将患者分为手术或非手术候选者,该算法纳入了六个加权标准:MRI检测到的半月板撕裂、外侧胫股骨挫伤、骨骼年龄、损伤机制和旋转松弛。对初始治疗的结果进行回顾性分析以验证算法。
75例患者中,55例(73.3%)接受了手术重建,20例(26.7%)接受了保守治疗。12例(60%)保守治疗失败,需要进行手术干预。该算法的回顾性应用在识别手术候选者方面的阳性预测值为91.7%,在成功保守治疗方面的阴性预测值为87.5%。
BABY-Knee算法在指导骨骼未成熟的急性ACL损伤患者的治疗决策方面显示出高度可靠性,在近90%的病例中预测了保守治疗的结果。需要进一步研究以确认其在更多前瞻性病例系列中的适用性。
IV级,病例系列。