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基于MRI和患者特征为骨骼未成熟的急性前交叉韧带损伤患者创建并验证一种治疗算法。

Creation and validation of a treatment algorithm for skeletally immature patients with acute anterior cruciate ligament injury based on MRI and patient characteristics.

作者信息

Grassi Alberto, Borque Kyle, Dietvorst Martijn, Altovino Emanuele, Rossi Claudio, Ambrosini Luca, Bondi Alice, Zaffagnini Stefano

机构信息

Dipartimento di Scienze Biomediche e Neuromotorie DIBINEM Università di Bologna Bologna Italy.

Clinica Ortopedica e Traumatologica II, Istituto Ortopedico Rizzoli Bologna Italy.

出版信息

J Exp Orthop. 2025 Aug 5;12(3):e70280. doi: 10.1002/jeo2.70280. eCollection 2025 Jul.

Abstract

PURPOSE

This study aimed to develop and validate a clinical decision-making algorithm, the 'Best ACL-treatment Based on the Years of the Knee' (BABY-Knee) Algorithm, for treating acute anterior cruciate ligament (ACL) injuries in skeletally immature patients. The algorithm integrates magnetic resonance imaging (MRI) findings and patient-specific characteristics to differentiate cases suitable for conservative management from those requiring surgical intervention.

METHODS

A prospective cohort of 75 skeletally immature patients (mean age: 13.9 ± 2.2 years) diagnosed with ACL rupture at a single institution between February 2022 and October 2024 was evaluated. Patients were categorized as surgical or non-surgical candidates based on the BABY-Knee Algorithm, which incorporates six weighted criteria: MRI-detected meniscal tears, lateral tibiofemoral bone bruises, skeletal age, injury mechanism and rotatory laxity. Outcomes of initial management were retrospectively analyzed for algorithm validation.

RESULTS

Of the 75 patients, 55 (73.3%) underwent surgical reconstruction, while 20 (26.7%) were managed conservatively. Conservative treatment failed in 12 cases (60%), necessitating surgical intervention. Retrospective application of the algorithm yielded a positive predictive value of 91.7% for identifying surgical candidates and a negative predictive value of 87.5% for successful conservative treatment.

CONCLUSION

The BABY-Knee Algorithm demonstrated high reliability in guiding treatment decisions for skeletally immature patients with acute ACL injuries, predicting outcomes of conservative treatment in nearly 90% of cases. Further studies are required to confirm its applicability in additional prospective case series.

LEVEL OF EVIDENCE

Level IV, case series.

摘要

目的

本研究旨在开发并验证一种临床决策算法,即“基于膝关节年龄的最佳前交叉韧带治疗”(BABY-Knee)算法,用于治疗骨骼未成熟患者的急性前交叉韧带(ACL)损伤。该算法整合了磁共振成像(MRI)结果和患者特定特征,以区分适合保守治疗的病例与需要手术干预的病例。

方法

对2022年2月至2024年10月期间在单一机构诊断为ACL断裂的75例骨骼未成熟患者(平均年龄:13.9±2.2岁)进行前瞻性队列研究。根据BABY-Knee算法将患者分为手术或非手术候选者,该算法纳入了六个加权标准:MRI检测到的半月板撕裂、外侧胫股骨挫伤、骨骼年龄、损伤机制和旋转松弛。对初始治疗的结果进行回顾性分析以验证算法。

结果

75例患者中,55例(73.3%)接受了手术重建,20例(26.7%)接受了保守治疗。12例(60%)保守治疗失败,需要进行手术干预。该算法的回顾性应用在识别手术候选者方面的阳性预测值为91.7%,在成功保守治疗方面的阴性预测值为87.5%。

结论

BABY-Knee算法在指导骨骼未成熟的急性ACL损伤患者的治疗决策方面显示出高度可靠性,在近90%的病例中预测了保守治疗的结果。需要进一步研究以确认其在更多前瞻性病例系列中的适用性。

证据水平

IV级,病例系列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cb4/12322690/11094461e5fe/JEO2-12-e70280-g001.jpg

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