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CB1 receptor and psychosis: friend, foe, or both.

作者信息

Rao Jagadeesh S, Tangarife Maria Alejandra, Rodríguez-Soacha Diego A, Mukunda Ram

机构信息

IGC Pharma Inc, Potomac, MD, United States.

出版信息

Front Psychiatry. 2025 Jul 22;16:1630080. doi: 10.3389/fpsyt.2025.1630080. eCollection 2025.

DOI:10.3389/fpsyt.2025.1630080
PMID:40766927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12322747/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fc/12322747/4414b7910773/fpsyt-16-1630080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fc/12322747/4414b7910773/fpsyt-16-1630080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fc/12322747/4414b7910773/fpsyt-16-1630080-g001.jpg

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本文引用的文献

1
Genetic overlap between schizophrenia spectrum disorders and Alzheimer's disease: Current evidence and future directions - An integrative review.精神分裂症谱系障碍与阿尔茨海默病的遗传重叠:当前证据与未来方向——综合述评。
Neurosci Biobehav Rev. 2024 Dec;167:105900. doi: 10.1016/j.neubiorev.2024.105900. Epub 2024 Sep 17.
2
The Endocannabinoid System in Alzheimer's Disease: A Network Meta-Analysis.阿尔茨海默病中的内源性大麻素系统:网络荟萃分析。
J Neurosci Res. 2024 Sep;102(9):e25380. doi: 10.1002/jnr.25380.
3
DNA methylation at cannabinoid type 1 and dopamine D2 receptor genes in saliva samples of psychotic subjects: Is there an effect of Cannabis use?
精神分裂症患者唾液样本中大麻素 1 型受体和多巴胺 D2 受体基因的 DNA 甲基化:大麻使用是否有影响?
Pharmacol Res. 2024 Oct;208:107343. doi: 10.1016/j.phrs.2024.107343. Epub 2024 Aug 8.
4
The Use of Dispensary-Obtained Tetrahydrocannabinol as a Treatment for Neuropsychiatric Symptoms of Dementia.使用药房获得的四氢大麻酚治疗痴呆的神经精神症状。
J Clin Psychiatry. 2023 Sep 18;84(6):23m14791. doi: 10.4088/JCP.23m14791.
5
Impact of Adolescent Cannabis Use on Neurocognitive and Brain Development.青少年使用大麻对神经认知和大脑发育的影响。
Child Adolesc Psychiatr Clin N Am. 2023 Jan;32(1):21-42. doi: 10.1016/j.chc.2022.06.002. Epub 2022 Oct 22.
6
Phytocannabinoids and schizophrenia: Focus on adolescence as a critical window of enhanced vulnerability and opportunity for treatment.植物大麻素与精神分裂症:聚焦于青春期作为增强易损性和治疗机会的关键窗口。
Pharmacol Res. 2021 Dec;174:105938. doi: 10.1016/j.phrs.2021.105938. Epub 2021 Oct 14.
7
Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats.精神分裂症中多巴胺 D2 和大麻素 CB1 受体转录调控的串扰:在患者和围产期 Δ9-四氢大麻酚暴露的大鼠中的分析。
Pharmacol Res. 2021 Feb;164:105357. doi: 10.1016/j.phrs.2020.105357. Epub 2020 Dec 4.
8
In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis.首发精神病患者大麻素 1 受体水平的体内可用性。
JAMA Psychiatry. 2019 Oct 1;76(10):1074-1084. doi: 10.1001/jamapsychiatry.2019.1427.
9
The Problem with the Current High Potency THC Marijuana from the Perspective of an Addiction Psychiatrist.从成瘾精神科医生的角度看当前高效力四氢大麻酚大麻的问题
Mo Med. 2018 Nov-Dec;115(6):482-486.
10
Genetic risk for schizophrenia and psychosis in Alzheimer disease.阿尔茨海默病中精神分裂症和精神病的遗传风险。
Mol Psychiatry. 2018 Apr;23(4):963-972. doi: 10.1038/mp.2017.81. Epub 2017 May 2.