Treitler Peter, Lloyd Kristen, Cantor Joel, Chakravarty Sujoy, Crystal Stephen, Kline Anna, Morton Cory, Powell Kristen Gilmore, Borys Suzanne, Cooperman Nina A
Boston University School of Social Work, Boston, MA.
Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ.
Ann Emerg Med. 2025 Aug 6. doi: 10.1016/j.annemergmed.2025.06.616.
To examine whether participation in the New Jersey Opioid Overdose Recovery Program (OORP), an emergency department-based peer recovery support service, was associated with drug treatment initiation and other postdischarge outcomes.
This retrospective cohort study used the 2015 to 2020 New Jersey Medicaid claims linked to OORP evaluation data. Outcomes during 180-day follow-up were compared between opioid overdoses among OORP participants and a propensity score-matched group of overdoses among nonparticipants. Outcomes included any medication for opioid use disorder initiation (primary), percentage of days covered with medication for opioid use disorder, psychosocial treatment initiation and engagement, repeat opioid and any drug overdose, and all-cause and opioid-related acute care utilization. Outcomes were assessed using linear regression (for medication for opioid use disorder percentage of days covered and psychosocial treatment engagement) and Cox proportional hazards (for all other outcomes) models.
A total of 7,109 overdose events among 5,475 patients were included (62.2% men; 28.1% Black, 8.0% Hispanic, 56.1% White; mean age: 40.1 years). OORP participants (N=1,383 events) initiated medication for opioid use disorder at higher rates than nonparticipants (15% versus 12%; hazard ratio [HR]=2.31, 95% confidence interval [CI] 1.55 to 3.45). OORP participation was also associated with greater medication for opioid use disorder percentage of days covered (3.56 percentage points, 95% CI 0.72 to 6.47), psychosocial treatment initiation (HR=1.73, 95% CI 1.13 to 2.65), and psychosocial treatment engagement (11.97 percentage points, 95% CI 7.23 to 16.73), and lower risk of all-cause acute care utilization (HR=0.83; 95% CI 0.72 to 0.97). The association of the program with repeat overdose and opioid-related ED or inpatient visits was not statistically significant.
Peer recovery support service can support treatment linkages following ED-treated opioid overdose. Additional efforts are needed to retain patients in medication for opioid use disorder long-term, to reduce their risk for repeat overdose.
探讨参与新泽西州阿片类药物过量恢复项目(OORP)这一基于急诊科的同伴恢复支持服务,是否与药物治疗启动及其他出院后结局相关。
这项回顾性队列研究使用了2015年至2020年与OORP评估数据相关联的新泽西州医疗补助索赔。对OORP参与者中的阿片类药物过量事件与倾向得分匹配的非参与者过量事件组在180天随访期间的结局进行比较。结局包括任何阿片类药物使用障碍药物治疗的启动(主要结局)、阿片类药物使用障碍药物覆盖天数的百分比、心理社会治疗的启动和参与、复发性阿片类药物及任何药物过量、全因及阿片类药物相关急性护理利用情况。使用线性回归(用于阿片类药物使用障碍药物覆盖天数百分比和心理社会治疗参与情况)和Cox比例风险模型(用于所有其他结局)评估结局。
共纳入5475例患者的7109次过量事件(男性占62.2%;黑人占28.1%,西班牙裔占8.0%,白人占56.1%;平均年龄:40.1岁)。OORP参与者(1383次事件)启动阿片类药物使用障碍药物治疗的比例高于非参与者(15%对12%;风险比[HR]=2.31,95%置信区间[CI]为1.55至3.45)。参与OORP还与更高的阿片类药物使用障碍药物覆盖天数百分比(3.56个百分点,95%CI为0.72至6.47)、心理社会治疗启动(HR=1.73,95%CI为1.13至2.65)和心理社会治疗参与(11.97个百分点,95%CI为7.23至16.73)相关,且全因急性护理利用风险较低(HR=0.83;95%CI为0.72至0.97)。该项目与复发性过量及阿片类药物相关急诊科就诊或住院就诊之间的关联无统计学意义。
同伴恢复支持服务可支持急诊科治疗阿片类药物过量后的治疗联系。需要进一步努力使患者长期坚持阿片类药物使用障碍药物治疗,以降低其复发性过量的风险。