Hönes Felix, Mihaljevic André L, Wulff Daniel, Archid Rami, Capobianco Ivan
Department of General, Visceral and Transplantation Surgery, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany.
Langenbecks Arch Surg. 2025 Aug 6;410(1):239. doi: 10.1007/s00423-025-03755-z.
Obesity is a major global health concern, with bariatric surgeries commonly performed to achieve significant weight loss, reduce obesity-associated morbidity and improve quality of life. The COVID-19 pandemic disrupted daily routines, impacting physical activity and eating behaviors, potentially affecting weight outcomes. This study aims to evaluate whether the COVID-19 lockdown influenced long-term weight loss outcomes in bariatric surgery patients by comparing three-year postoperative results between patients who had surgery immediately before the lockdown and those who had surgery up to two years earlier.
A retrospective cohort analysis was conducted at the University Hospital of Tuebingen. Patients were categorized into two groups: the pandemic group (surgery from October 2019 to March 2020) and the pre-pandemic group (surgery from October 2017 to March 2019). The primary outcome was weight loss, while secondary outcomes included cholesterol levels, HbA1c, and long-term complications like reflux, gallstones, and gastrointestinal bleeding. Follow-up assessments were conducted at 6 months, 1 year, 2 years, and 3 years.
A total of 194 patients were analyzed. Sleeve gastrectomy was performed in 72% of cases, and gastric bypasses in 28%. No significant differences were found between groups in demographics, surgical technique distribution, or follow-up rates. Weight, BMI, and excess weight loss were comparable between the two groups, with stabilization observed between 88 and 90 kg and 30–32 kg/m² from one to three years post-surgery. Complication rates and laboratory parameters (cholesterol, HbA1c, parathyroid hormone) showed no significant differences between the groups.
The COVID-19 pandemic did not significantly affect long-term weight loss outcomes or metabolic parameters in bariatric surgery patients up to three years postoperatively. These findings suggest that despite lifestyle disruptions due to the lockdown bariatric surgery remains effective for sustained weight management.
肥胖是一个全球性的主要健康问题,减肥手术通常用于实现显著的体重减轻、降低肥胖相关疾病的发病率并改善生活质量。2019年冠状病毒病(COVID-19)大流行扰乱了日常生活,影响了身体活动和饮食行为,可能影响体重结果。本研究旨在通过比较在封锁前立即接受手术的患者与提前两年接受手术的患者的三年术后结果,评估COVID-19封锁是否影响减肥手术患者的长期体重减轻结果。
在图宾根大学医院进行了一项回顾性队列分析。患者被分为两组:大流行组(2019年10月至2020年3月接受手术)和大流行前组(2017年10月至2019年3月接受手术)。主要结果是体重减轻,次要结果包括胆固醇水平、糖化血红蛋白(HbA1c)以及反流、胆结石和胃肠道出血等长期并发症。在6个月、1年、2年和3年进行随访评估。
共分析了194例患者。72%的病例进行了袖状胃切除术,28%进行了胃旁路手术。两组在人口统计学、手术技术分布或随访率方面未发现显著差异。两组之间体重、体重指数(BMI)和超重减轻情况相当,术后1至3年体重稳定在88至90千克,BMI稳定在30 - 32千克/平方米。两组之间的并发症发生率和实验室参数(胆固醇、HbA1c、甲状旁腺激素)无显著差异。
COVID-19大流行对减肥手术患者术后三年的长期体重减轻结果或代谢参数没有显著影响。这些发现表明,尽管封锁导致生活方式中断,但减肥手术对于持续体重管理仍然有效。