Baudo F, de Cataldo F, Gatti R, Landonio G, Muti G, Scolari G
Haemostasis. 1985;15(6):402-4. doi: 10.1159/000215180.
Tooth extraction was carried out in 405 patients with various hemostatic disorders due to thrombocytopenia, chronic liver disease, hemophilia A and B, von Willebrand's disease and oral anticoagulants. Human fibrinogen concentrate was used as local hemostatic agent. Prophylactic replacement therapy (platelets or plasma concentrates) and antifibrinolytic agents were not administered. Oral anticoagulants were not discontinued. Minor postextraction bleeding occurred only in severe hemophilia A and occasionally in the oral anticoagulant group.
对405例因血小板减少、慢性肝病、甲型和乙型血友病、血管性血友病以及口服抗凝剂导致各种止血障碍的患者进行了拔牙手术。使用人纤维蛋白原浓缩物作为局部止血剂。未进行预防性替代治疗（血小板或血浆浓缩物）和抗纤维蛋白溶解剂治疗。口服抗凝剂未停用。拔牙后轻微出血仅发生在重度甲型血友病患者中，偶尔也出现在口服抗凝剂组中。
