Soetisna Tri Wisesa, Pajala Fegita Beatrix, Wartono Dicky Aligheri, Hanafy Dudy Arman, Tjubandi Amin
Adult Cardiac Surgery Division, Department of Thoracic and Cardiovascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Adult Cardiac Surgery Division, Department of Thoracic and Cardiovascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Int J Surg Case Rep. 2025 Jul 22;134:111718. doi: 10.1016/j.ijscr.2025.111718.
Aortic coarctation (CoA) is relatively rare in adult patients and often presents with non-specific symptoms. It typically results from either delayed recognition or residual lesion following incomplete repair in childhood. While concomitant cardiac abnormalities are commonly detected in children, adult patients more often present with isolated CoA or complications resulting from late diagnosis. Untreated CoA can lead to significant long-term complications, including refractory hypertension, heart failure, and aortic aneurysm or rupture.
We present a case series of three adult patients with CoA of varying severity and associated cardiac pathologies. Each patient underwent a different open surgical approach. First, a 39-year-old male presented with recurrent CoA with severe adhesions. Second, a 48-year-old male presented with proximal descending CoA accompanied by ascending aortic aneurysm and severe aortic stenosis. Third, a 25-year-old male presented with CoA and severe aortic valve insufficiency. All patients were diagnosed with CoA via echocardiography and underwent surgical procedures.
Managing adult CoA, particularly when combined with other cardiac pathologies, poses significant surgical challenges due to the lack of standardized guidelines for such complex conditions. Surgeons must make critical decisions regarding the order of repairs, the selection of the most suitable surgical approach, and the ideal timing of intervention to ensure patient safety.
Surgical approaches for CoA are individualized based on the complexity of the coarctation and associated cardiac pathologies. Surgical management of CoA either in adults or neonates should be performed accurately and effectively to reduce morbidity and long-term complications.
主动脉缩窄(CoA)在成年患者中相对少见,且常表现为非特异性症状。它通常是由于儿童期修复不完全导致的识别延迟或残留病变所致。虽然儿童中常检测到合并的心脏异常,但成年患者更常表现为孤立性CoA或因诊断延迟导致的并发症。未经治疗的CoA可导致严重的长期并发症,包括难治性高血压、心力衰竭以及主动脉瘤或破裂。
我们呈现了一组包含三名成年CoA患者的病例系列,他们的病情严重程度各异且伴有相关心脏病变。每位患者都接受了不同的开放手术方法。首先,一名39岁男性表现为复发性CoA且伴有严重粘连。其次,一名48岁男性表现为降主动脉近端CoA,伴有升主动脉瘤和严重主动脉狭窄。第三,一名25岁男性表现为CoA和严重主动脉瓣关闭不全。所有患者均通过超声心动图诊断为CoA并接受了手术治疗。
由于缺乏针对此类复杂情况的标准化指南,处理成年CoA,尤其是合并其他心脏病变时,会带来重大的手术挑战。外科医生必须就修复顺序、最合适手术方法的选择以及理想的干预时机做出关键决策,以确保患者安全。
CoA的手术方法根据缩窄及相关心脏病变的复杂性进行个体化选择。无论是成年患者还是新生儿,CoA的手术管理都应准确有效,以降低发病率和长期并发症。