Langenbucher Achim, Wendelstein Jascha, Cayless Alan, Hoffmann Peter, Szentmáry Nóra
Department of Experimental Ophthalmology, Saarland University, Homburg, Saar, Germany.
Department of Experimental Ophthalmology, Saarland University, Homburg, Saar, Germany; Department of Ophthalmology, Ludwig-Maximilian-University Clinics, Munich, Germany.
Z Med Phys. 2025 Aug 6. doi: 10.1016/j.zemedi.2025.07.004.
To develop, implement and demonstrate a calculation strategy to derive the best shape spherical or aspherical intraocular lens (IOL) considering corneal spherical aberration (SA).
The simulation concept is based on 2D raytracing and involves an ideal plano or spherical wavefront with an optical path length correction which simulates corneal SA. The IOL defined with its equivalent power PIOL, Coddington shape factor (CSF) and edge thickness (ET) could be located with its secondary principal plane (PP2) or its haptic plane (HP) at the predicted axial lens position (ELP).The lens geometry is optimised for the root-mean-squared wavefront error (RMSWF) and the best wavefront and rayscatter focus are derived.
The custom simulation software package is written in Matlab (version 2024a). The applicability of the simulation software is shown with some examples to show the performance of the results. The simulation results are structured to give some insight into best shape spherical and aspheric lenses, the impact of CSF, corneal spherical aberration to be corrected, and the concept of using the ELP to predict either the PP2 or the HP of the lens.
The simulation tool seems to be very robust in optimising best shape spherical and aspherical lenses based on available data for corneal power and spherical aberration. In all examples the spherical aberrations were completely eliminated or reduced to a negligible amount using individually shaped biconvex aspheric IOLs. An implementation in an industrial manufacturing process of customised aspheric lenses and a clinical study are needed to validate the concept in a clinical setting.
开发、实施并演示一种计算策略，以得出考虑角膜球差（SA）的最佳形状的球面或非球面人工晶状体（IOL）。
模拟概念基于二维光线追踪，涉及具有光程长度校正的理想平面或球面波前，以模拟角膜球差。通过其等效屈光力PIOL、科丁顿形状因子（CSF）和边缘厚度（ET）定义的人工晶状体，其第二主平面（PP2）或触觉平面（HP）可位于预测的轴向晶状体位置（ELP）。针对均方根波前误差（RMSWF）对晶状体几何形状进行优化，并得出最佳波前和光线散射焦点。
定制的模拟软件包用Matlab（版本2024a）编写。通过一些示例展示了模拟软件的适用性，以说明结果的性能。模拟结果的结构有助于深入了解最佳形状的球面和非球面晶状体、CSF的影响、待校正的角膜球差以及使用ELP预测晶状体的PP2或HP的概念。
基于角膜屈光力和球差的可用数据，该模拟工具在优化最佳形状的球面和非球面晶状体方面似乎非常强大。在所有示例中，使用单独塑形的双凸非球面人工晶状体可完全消除球差或将其降低到可忽略的程度。需要在定制非球面晶状体的工业制造过程中实施并进行临床研究，以在临床环境中验证该概念。
