[Diogenes syndrome].

Endogenous or physically conditioned psychoses are usually considered to be the underlying cause of signs of extreme self-neglect and social retreat if these occur suddenly in persons who had been socially successful up to that time. However, in recent years several independent researchers have found extreme sociocultural refusal attitudes even in patients not displaying any psychotic disturbances. This unexpected result led to a new syndrome concept which has since been accepted internationally under the designation "Diogenes syndrome". Hence, the Diogenes syndrome comprises shameless neglect of body and personal environment, associated with collectionism, social retreat and rejection of any well-meant help. It has been reported that this constellation of signs allegedly occurs with enhanced frequency in women over 60 years of age with self-isolation tendencies in their previous life history. The following article reviews the literature published so far on the Diogenes syndrome and presents two cases treated by the authors, as a suitable means to re-examine and to define the new syndrome concept more precisely. The following conclusions can be drawn from the cases already reported in the literature and the two cases newly presented here: The socioculturally complete rejection associated with the Diogenes syndrome is the final result of a personality-based abnormal emotional reaction development. Marked seclusion tendencies in the previous life history, as well as organic brain diseases, are relevant. Medical treatment can be successful mainly by means of behaviour therapy techniques.