Wu Xixi, Cheng Linbo, Zhang Shimao, Lu Yu, Wang Tao, Su Mi, Yuan Qinqin, Ge Huisheng
Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Front Pediatr. 2025 Jul 23;13:1612488. doi: 10.3389/fped.2025.1612488. eCollection 2025.
The placenta is a highly specialized temporary organ during pregnancy. As the hinge of material exchange between mother and fetus, it plays a crucial role in maintaining the fetus's intrauterine life and growth period of fetus. Placental lesions or dysfunction can cause pregnancy diseases. Placental chorioangioma is a benign tumor originating from the placental with an incidence rate of 1%, whose etiology has not yet been fully elucidated. Prenatal diagnosis can usually be done by clinical ultrasound. However, placental chorioangiomatosis, as a placental choriovascular disease, is rarely reported or studied at home and abroad. Due to the unclear etiology and pathogenesis, prenatal diagnosis of placental chorioangiomatosis before early recognition of severe maternal and fetal complications during pregnancy is sparse. Therefore, patients cannot be effectively treated, and pregnancy outcomes are often poor. Herein we provide a case at our hospital and conduct a series of literature reviews around this case to further improve the understanding of placental chorioangiomatosis, and promote early recognition and early intervention.
胎盘是孕期一个高度特化的临时器官。作为母胎之间物质交换的枢纽,它在维持胎儿的宫内生活及胎儿生长发育过程中发挥着关键作用。胎盘病变或功能障碍可引发妊娠疾病。胎盘绒毛膜血管瘤是一种起源于胎盘的良性肿瘤,发病率为1%,其病因尚未完全阐明。产前诊断通常可通过临床超声进行。然而,胎盘绒毛膜血管瘤病作为一种胎盘绒毛血管疾病,在国内外鲜有报道和研究。由于病因及发病机制尚不明确,在孕期早期识别严重母婴并发症之前,胎盘绒毛膜血管瘤病的产前诊断较为少见。因此,患者无法得到有效治疗,妊娠结局往往较差。在此,我们提供我院的一个病例,并围绕该病例进行一系列文献综述,以进一步加深对胎盘绒毛膜血管瘤病的认识,促进早期识别和早期干预。