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先兆子痫中多灶性脉络膜血管瘤病与间充质发育异常的共存。

Co-occurrence of multifocal chorioangiomatosis and mesenchymal dysplasia in preeclampsia.

作者信息

Rosefort Audrey, Cordier Anne-Gael, Kaddioui Sahar, Beaumont Brigitte, Baergen Rebecca, Benachi Alexandra, Martinovic Jelena

机构信息

Department of Obstetrics and Gynecology, Antoine Béclère Hospital, Paris-Sud University, Clamart, France.

出版信息

Pediatr Dev Pathol. 2013 May-Jun;16(3):206-9. doi: 10.2350/12-02-1153-CR.1. Epub 2013 Jan 3.

DOI:10.2350/12-02-1153-CR.1
PMID:23286309
Abstract

Chorioangioma is the most common benign vascular placental tumor. It is often small and has no clinical significance. Large chorioangiomata are rarer and can lead to fetal or maternal complications. Chorioangiomatosis is even rarer and is defined as a focal or multifocal proliferation of placental capillaries permeating villous tissue. Placental mesenchymal dysplasia (PMD) is characterized by the overgrowth of placental mesenchymal tissue and can be associated with fetal or obstetrical complications. We report a case associated with preeclampsia and intrauterine growth restriction, in which both chorioangiomatosis and PMD were present.

摘要

绒毛膜血管瘤是最常见的良性胎盘血管肿瘤。它通常较小,无临床意义。较大的绒毛膜血管瘤较为罕见,可导致胎儿或母体并发症。绒毛膜血管瘤病更为罕见,定义为弥漫性或多灶性胎盘毛细血管增生并侵入绒毛组织。胎盘间充质发育异常(PMD)的特征是胎盘间充质组织过度生长,可伴有胎儿或产科并发症。我们报告一例与子痫前期和胎儿生长受限相关的病例,该病例同时存在绒毛膜血管瘤病和PMD。

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1
Co-occurrence of multifocal chorioangiomatosis and mesenchymal dysplasia in preeclampsia.先兆子痫中多灶性脉络膜血管瘤病与间充质发育异常的共存。
Pediatr Dev Pathol. 2013 May-Jun;16(3):206-9. doi: 10.2350/12-02-1153-CR.1. Epub 2013 Jan 3.
2
Microangiopathic hemolytic anemia and thrombocytopenia in a neonate associated with a large placental chorioangioma.一名新生儿出现微血管病性溶血性贫血和血小板减少症,与巨大胎盘绒毛膜血管瘤有关。
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Placental mesenchymal dysplasia and fetal hematologic disorder.胎盘间充质发育异常与胎儿血液系统疾病。
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引用本文的文献

1
Placental chorioangiomatosis: a case report and literature review.胎盘绒毛膜血管瘤:一例报告及文献综述。
Front Pediatr. 2025 Jul 23;13:1612488. doi: 10.3389/fped.2025.1612488. eCollection 2025.
2
A giant early second-trimester placental chorioangioma associated with isolated proteinuria and histopathologically confirmed placental insufficiency, a novel association: A case report.一例巨大的孕中期早期胎盘绒毛膜血管瘤,伴有孤立性蛋白尿且经组织病理学证实存在胎盘功能不全,一种新的关联:病例报告
Clin Case Rep. 2022 Mar 16;10(3):e05605. doi: 10.1002/ccr3.5605. eCollection 2022 Mar.