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[已撤回] 微小RNA-181a通过靶向耐药肺腺癌细胞中的PTEN调控上皮-间质转化

[Retracted] MicroRNA‑181a regulates epithelial‑mesenchymal transition by targeting PTEN in drug‑resistant lung adenocarcinoma cells.

作者信息

Li Haihui, Zhang Pei, Sun Xiaojin, Sun Yiming, Shi Chao, Liu Hao, Liu Xuegang

机构信息

Shandong University, Jinan, Shandong, P.R. China.

Faculty of Pharmacy, Bengbu Medical College, Bengbu, Anhui, P.R. China.

出版信息

Int J Oncol. 2025 Oct;67(4). doi: 10.3892/ijo.2025.5784. Epub 2025 Aug 8.

Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the scratch wound and cell migration and invasion assay experiments shown in Fig. 2A and B and Fig. 5A‑C, a large number of data panels showed evidence of overlapping data, both within the same figure parts and comparing between figures. Similarly, evidence was also uncovered of data duplication comparing the cell microscopic images in Figs. 6A, 7B and 8B. Owing to the large number of data duplication events that have been identified in this paper, the Editor of has decided that it should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 47: 1379‑1392, 2015; DOI: 10.3892/ijo.2015.3144].

摘要

上述论文发表后,一位关注此事的读者提醒编辑注意,关于图2A和B以及图5A - C所示的划痕伤口以及细胞迁移和侵袭试验实验,大量数据面板显示出在同一图的不同部分以及不同图之间存在数据重叠的迹象。同样,在比较图6A、7B和8B中的细胞显微图像时,也发现了数据重复的证据。由于本文中已发现大量数据重复事件,《国际肿瘤学杂志》的编辑决定,鉴于对所呈现数据缺乏信心,应从该期刊撤回此论文。已要求作者对这些问题作出解释,但编辑部未收到回复。编辑就由此造成的不便向读者致歉。[《国际肿瘤学杂志》47: 1379 - 1392, 2015; DOI: 10.3892/ijo.2015.3144]

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