Pham Hoang Nhat, Abdelnabi Mahmoud H, Ibrahim Ramzi, Sainbayar Enkhtsogt, Truong Hong Hieu, Habib Eiad, Pathangey Girish, Bcharah George, Singh Amitoj, Arsanjani Reza, Chahal Anwar A, Sorajja Dan
Department of Medicine, University of Arizona, Tucson, AZ 85721, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55901, USA.
Rev Cardiovasc Med. 2025 Jul 28;26(7):39200. doi: 10.31083/RCM39200. eCollection 2025 Jul.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, contributing to significant morbidity and mortality worldwide. The relationship between physical exercise and AF is complex, with studies showing both beneficial and potentially adverse effects. Moreover, evidence suggests a U-shaped association between exercise intensity and AF risk. Moderate exercise has been shown to reduce AF burden by improving cardiovascular risk factors, enhancing autonomic regulation, and mitigating atrial fibrosis. In contrast, excessively high-intensity endurance exercise may increase AF risk, particularly in young athletes, due to atrial stretching, dilation, fibrosis, autonomic imbalances, and heightened inflammation. The current guidelines emphasize exercise as a core lifestyle intervention for AF management, recommending moderate-intensity aerobic activity for optimal outcomes. This review examines the current evidence on the effects of exercise on AF, identifies knowledge gaps, and proposes potential future research directions.
心房颤动（AF）是最常见的持续性心律失常，在全球范围内导致了显著的发病率和死亡率。体育锻炼与房颤之间的关系很复杂，研究表明既有有益影响，也有潜在的不利影响。此外，有证据表明运动强度与房颤风险之间呈U形关联。适度运动已被证明可通过改善心血管危险因素、增强自主神经调节和减轻心房纤维化来减轻房颤负担。相比之下，过高强度的耐力运动可能会增加房颤风险，尤其是在年轻运动员中，这是由于心房拉伸、扩张、纤维化、自主神经失衡和炎症加剧所致。当前指南强调运动是房颤管理的核心生活方式干预措施，推荐中等强度的有氧运动以获得最佳效果。本综述探讨了运动对房颤影响的当前证据，识别了知识空白，并提出了未来潜在的研究方向。
