Chi Nguyen Thi Thanh, Ly Nguyen Tran Huong, Hieu Doan Duc, Van Meervelt Luc
Department of Chemistry, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi, Vietnam.
Department of Chemistry, KU Leuven, Biomolecular Architecture, Celestijnenlaan 200F, Leuven (Heverlee), B-3001, Belgium.
Acta Crystallogr E Crystallogr Commun. 2025 Jul 1;81(Pt 8):657-661. doi: 10.1107/S2056989025005766. eCollection 2025 Aug 1.
The title complex, [Pt(CHNO)Cl(CHP)], was synthesized by the reaction of [PtCl(CHNO)(η-CH)] and PCy at room temperature for 2 h with a yield of 80%. The deprotonated 5-nitro-quinoline-8-ol (CHNO ) anion coordinates to the metal atom in a bidentate mode its N and O atoms with a N-Pt-O bite angle of 80.0 (3)°. The tri-cyclo-hexyl-phosphine P atom is in a position with respect to the N atom in the square-planar coordination environment of the metal atom. The packing features zigzag chains linked by C-H⋯O inter-actions and continuous channels occupied by disordered solvent mol-ecules, both running in the -axis direction. The complex shows weak activity against four cancer cell lines with IC values > 120 µ, but significant catalytic ability and selectivity for hydro-silylation between phenyl-acetyl-ene and tri-ethyl-silane.
标题配合物[Pt(CHNO)Cl(CHP)]是通过[PtCl(CHNO)(η-CH)]与PCy在室温下反应2小时合成的，产率为80%。去质子化的5-硝基喹啉-8-醇(CHNO)阴离子以双齿模式通过其N和O原子与金属原子配位，N-Pt-O咬角为80.0(3)°。在金属原子的平面正方形配位环境中，三环己基膦P原子相对于N原子处于一个位置。堆积特征是通过C-H⋯O相互作用连接的锯齿链和由无序溶剂分子占据的连续通道，两者都沿轴方向延伸。该配合物对四种癌细胞系显示出较弱的活性，IC值>120 µ，但对苯乙炔和三乙基硅烷之间的硅氢化反应具有显著的催化能力和选择性。
