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一名曾接受主动脉移植手术的患者在反复出现胃肠道出血后被诊断为继发性主动脉十二指肠瘘。

Secondary Aortoduodenal Fistula Diagnosed after Repeated Gastrointestinal Bleeding Episodes in a Patient With Prior Aortic Graft Surgery.

作者信息

Kubota Jun, Ichita Chikamasa, Nakaya Soichiro, Nishino Takashi, Sumida Chihiro, Sasaki Akiko, Hama Daisuke

机构信息

Gastroenterology Medicine Center Shonan Kamakura General Hospital Kanagawa Japan.

Department of Cardiovascular Surgery Shonan Kamakura General Hospital Kanagawa Japan.

出版信息

DEN Open. 2025 Aug 6;6(1):e70181. doi: 10.1002/deo2.70181. eCollection 2026 Apr.

DOI:10.1002/deo2.70181
PMID:40777737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12328087/
Abstract

Secondary aortoduodenal fistula (sADF) is a rare but life-threatening complication after aortic graft surgery. Diagnosis is often challenging, particularly when contrast-enhanced computed tomography (CT) and endoscopy results are inconclusive. We report a case in which diagnosis was challenging due to contrast media allergy and non-diagnostic endoscopic findings, highlighting the importance of clinical suspicion in such scenarios. A 76-year-old man with a history of graft replacement for a ruptured abdominal aortic aneurysm presented with five episodes of gastrointestinal bleeding over 3 months. Despite multiple examinations, no bleeding source was identified. Eventually, after the patient developed hypovolemic shock, contrast-enhanced CT was performed with informed consent, which revealed contrast extravasation from the aorta into the horizontal portion of the duodenum. Endoscopy subsequently identified an exposed vessel in the same location, confirming the diagnosis of sADF. Endovascular aortic repair was successfully performed. This case underscores the need to consider sADF in patients with aortic grafts who present with recurrent, unexplained gastrointestinal bleeding.

摘要

继发性主动脉十二指肠瘘(sADF)是主动脉移植手术后一种罕见但危及生命的并发症。诊断往往具有挑战性,尤其是当增强计算机断层扫描(CT)和内镜检查结果不明确时。我们报告一例因造影剂过敏和内镜检查无诊断性结果而使诊断具有挑战性的病例,强调在此类情况下临床怀疑的重要性。一名76岁男性,有腹主动脉瘤破裂移植置换史,在3个月内出现5次胃肠道出血。尽管进行了多次检查,但未发现出血源。最终,在患者发生低血容量性休克后,经知情同意进行了增强CT检查,结果显示造影剂从主动脉渗入十二指肠水平部。随后内镜检查在同一位置发现了暴露的血管,确诊为sADF。成功进行了血管腔内主动脉修复术。该病例强调,对于有主动脉移植史且出现反复不明原因胃肠道出血的患者,需要考虑sADF。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ed/12328087/167dd4766143/DEO2-6-e70181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ed/12328087/646a4f05d576/DEO2-6-e70181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ed/12328087/167dd4766143/DEO2-6-e70181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ed/12328087/646a4f05d576/DEO2-6-e70181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ed/12328087/167dd4766143/DEO2-6-e70181-g001.jpg

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本文引用的文献

1
The Role of Imaging for Gastrointestinal Bleeding: Consensus Recommendations From the American College of Gastroenterology and Society of Abdominal Radiology.《影像学在胃肠道出血中的作用:美国胃肠病学会和腹部放射学会的共识推荐》
Am J Gastroenterol. 2024 Mar 1;119(3):438-449. doi: 10.14309/ajg.0000000000002631. Epub 2023 Oct 4.
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Recent advances in clinical practice: advances in cross-sectional imaging in inflammatory bowel disease.临床实践新进展:炎症性肠病的横断面成像进展。
Gut. 2022 Dec;71(12):2587-2597. doi: 10.1136/gutjnl-2021-326562. Epub 2022 Aug 4.
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Improved perioperative mortality after secondary aortoenteric fistula repair and lessons learned from a 20-year experience.
二次主动脉肠瘘修复术后围手术期死亡率的改善和 20 年经验教训。
J Vasc Surg. 2022 Jan;75(1):287-295.e3. doi: 10.1016/j.jvs.2021.07.107. Epub 2021 Jul 22.
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Ann Vasc Surg. 2016 Oct;36:28-34. doi: 10.1016/j.avsg.2016.03.028. Epub 2016 Jul 15.
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Early and late results of contemporary management of 37 secondary aortoenteric fistulae.37 例继发性胸主动脉肠瘘的当代治疗的早期和晚期结果。
Eur J Vasc Endovasc Surg. 2011 Jun;41(6):748-57. doi: 10.1016/j.ejvs.2011.02.020. Epub 2011 Mar 16.
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Enigma of primary aortoduodenal fistula.原发性主动脉十二指肠瘘之谜。
World J Gastroenterol. 2009 Jul 7;15(25):3191-3. doi: 10.3748/wjg.15.3191.
8
Primary aortoenteric fistula.原发性主动脉肠瘘
Br J Surg. 2005 Feb;92(2):143-52. doi: 10.1002/bjs.4928.
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Primary aortoenteric fistula: report of eight new cases and review of the literature.原发性主动脉肠瘘:8例新病例报告及文献复习
Ann Vasc Surg. 1996 Jan;10(1):40-8. doi: 10.1007/BF02002340.