突尼斯活产儿先天性畸形的流行病学：一项回顾性研究。
Epidemiology of congenital malformations in Tunisian liveborns: a retrospective study.
作者信息
Nasri Kaouther, Ben Jamaa Nadia, Aloui Mariem, Mansouri Safouane, Sdiri Yosra, Cheour Mariem, Kacem Samia
机构信息
Faculty of Sciences of Bizerte, University of Carthage, 7021 Zarzouna, Bizerte, Tunisia.
Department of Embryo-Fetopathology, Center for Maternity and Neonatology of Tunis, Tunis El Manar University, 1007 Tunis, Tunisia.
出版信息
Afr Health Sci. 2024 Sep;24(3):333-344. doi: 10.4314/ahs.v24i3.37.
OBJECTIVE
To identify the various congenital malformations in liveborns in the neonatology service within the center of maternity and neonatology of Tunis (CMNT).
METHODS
This is a retrospective study of liveborns with congenital malformations hospitalized during one year from 1rst January to 31 December 2016.
RESULTS
The profile of malformations was dominated by polymalformations (22.29%), followed by chromosomal aberrations (21.14%), cardiovascular malformations (16.00%), and system nervous malformations (11.43%).Comparisons of liveborns and parental characteristics between all congenital malformations subtypes have shown significant differences in liveborns sex, consanguinity, and maternal age. Comparisons between malformed newborns and malformed fetuses have shown significant differences in consanguinity, rhesus type, maternal origin and parity.
CONCLUSION
It seems important to set a careful surveillance of pregnancies at risk of developing congenital anomalies, systematic supplementation of vitamins and folic acid, and a national registry of congenital malformations.
目的
确定突尼斯妇产及新生儿中心（CMNT）新生儿科活产儿中的各种先天性畸形。
方法
这是一项对2016年1月1日至12月31日期间住院的患有先天性畸形的活产儿进行的回顾性研究。
结果
畸形特征以多发畸形为主（22.29%），其次是染色体畸变（21.14%）、心血管畸形（16.00%）和神经系统畸形（11.43%）。所有先天性畸形亚型的活产儿与父母特征比较显示，活产儿性别、近亲结婚情况和母亲年龄存在显著差异。畸形新生儿与畸形胎儿的比较显示，近亲结婚情况、恒河猴血型、母亲籍贯和产次存在显著差异。
结论
对有发生先天性异常风险的妊娠进行仔细监测、系统补充维生素和叶酸以及建立全国先天性畸形登记册似乎很重要。
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