Kunzová Monika, Lagová Eliška, Keith Leslyn
Department of Public Health, Faculty of Medicine, Masaryk University, Brno, Czechia.
International Clinical Research Center (ICRC), St Anne's University Hospital (FNUSA), Brno, Czechia.
Front Glob Womens Health. 2025 Jul 24;6:1629077. doi: 10.3389/fgwh.2025.1629077. eCollection 2025.
Lipedema is a chronic condition characterized by excessive fat deposition in the hips, buttocks, and lower legs, significantly impacting quality of life. In Czechia, limited research exists on the relationship between lipedema symptoms and depressive symptoms, despite the condition's prevalence and its impact on mental health.
This study aims to investigate the relationship between lipedema symptoms and the severity of depressive symptoms among Czech women and assess their quality of life.
We administered an online survey to 43 women with lipedema. Participants completed questionnaires on quality of life (WHOQOL-BREF), sociodemographic and clinical characteristics, and depressive symptoms severity, evaluated using the PHQ-9 tool.
PHQ-9 results showed that 50.9% of participants exhibited moderate to severe depressive symptoms. Quality of life ratings varied, with 27.9% of participants rating their health as poor or very poor. Significant correlations were found between lipedema symptoms, such as shortness of breath, muscle stiffness, and depression severity, indicating a complex relationship between physical symptoms and mental health.
These findings highlight the significant mental health burden faced by individuals with lipedema. The association between physical and depressive symptoms emphasizes the need for comprehensive, tailored interventions, especially integrated mental and physical healthcare approaches, aimed at improving overall well-being in this population.
脂肪性水肿是一种慢性病,其特征是髋部、臀部和小腿出现过多脂肪沉积,对生活质量有显著影响。在捷克,尽管脂肪性水肿较为普遍且对心理健康有影响,但关于脂肪性水肿症状与抑郁症状之间关系的研究有限。
本研究旨在调查捷克女性中脂肪性水肿症状与抑郁症状严重程度之间的关系,并评估她们的生活质量。
我们对43名患有脂肪性水肿的女性进行了在线调查。参与者完成了关于生活质量(世界卫生组织生活质量简表)、社会人口统计学和临床特征以及抑郁症状严重程度的问卷,抑郁症状严重程度使用PHQ-9工具进行评估。
PHQ-9结果显示,50.9%的参与者表现出中度至重度抑郁症状。生活质量评分各不相同,27.9%的参与者将自己的健康评为差或非常差。在脂肪性水肿症状(如呼吸急促、肌肉僵硬)与抑郁严重程度之间发现了显著相关性,表明身体症状与心理健康之间存在复杂关系。
这些发现凸显了脂肪性水肿患者所面临的重大心理健康负担。身体症状与抑郁症状之间的关联强调了需要采取全面、量身定制的干预措施,特别是综合的身心医疗保健方法,以改善这一人群的整体健康状况。