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CHADS-VASc评分可预测急性ST段抬高型心肌梗死情况下的无复流现象。

CHADS-VASc Score can predict no-reflow in the settings of acute ST-elevated myocardial infarction.

作者信息

Karabay K Ocal, Bagirtan Bayram, Ozdemir Behzat, Tozlu Busra, Bayram Muhammed, Pirinc Sati Selda, Cetin Sukru, Demiroz Onder

机构信息

Department of Cardiology, Sehit Prof.Dr. Ilhan Varank Research and Education Hospital, Istanbul, Turkey. Email:

Department of Cardiology, Sehit Prof.Dr. Ilhan Varank Research and Education Hospital, Istanbul, Turkey.

出版信息

Cardiovasc J Afr. 2025 Jun 30;36(2):150-153. doi: 10.5830/CVJA-2025-014. Epub 2025 Jun 23.

Abstract

BACKGROUND

No-reflow (NR) is one of the serious complications of primary percutaneous coronary intervention (PCI) and it is related to higher short- and long-term mortality. In this study, we aim to determine NR possibility with a scoring system.

METHODS

This retrospective, single-center study included consecutive patients diagnosed with acute ST- segment elevation myocardial infarction (STEMI) and treated by PCI, between May 2019 and May 2024.

RESULTS

A total 1050 patients were included: patients were divided to two groups according to the final coronary flow: NR group ( = 139) and control group ( = 930). CHADS-VASc score was calculated for all the patients and multivariable regression and receiver operating characteristic curve analyses were conducted to determine the independent predictors of NR and cut-off value of CHAD-VASc score. CHAD-VASc cut-off values of 2 have a sensitivity of 84.2% and a specificity of 30% (The area under the curve (AUC) was calculated to be 0.615).

CONCLUSION

A CHADS-VASc score ≥ 2 may serve as a valuable predictive tool for identifying the occurrence of NR in patients with STEMI. The sensitivity demonstrated in our study offers clinicians a practical approach for risk stratification and management of patients at risk of developing NR.

摘要

背景

无复流(NR)是直接经皮冠状动脉介入治疗(PCI)的严重并发症之一,与较高的短期和长期死亡率相关。在本研究中,我们旨在通过一种评分系统确定无复流的可能性。

方法

这项回顾性单中心研究纳入了2019年5月至2024年5月期间连续诊断为急性ST段抬高型心肌梗死(STEMI)并接受PCI治疗的患者。

结果

共纳入1050例患者:根据最终冠状动脉血流情况将患者分为两组:无复流组(n = 139)和对照组(n = 930)。计算所有患者的CHADS-VASc评分,并进行多变量回归和受试者工作特征曲线分析,以确定无复流的独立预测因素和CHADS-VASc评分的截断值。CHADS-VASc截断值为2时,敏感性为84.2%,特异性为30%(曲线下面积(AUC)计算为0.615)。

结论

CHADS-VASc评分≥2可作为识别STEMI患者无复流发生的有价值预测工具。我们研究中显示的敏感性为临床医生提供了一种对有发生无复流风险的患者进行风险分层和管理的实用方法。

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