Jensen B L
J Craniofac Genet Dev Biol. 1985;5(4):327-40.
The aim of the present investigation was to analyze craniofacial morphology in adults with Turner syndrome and to compare the morphology in patients with 45,X karyotypes to that found in subjects with other X-chromosome aberrations. A comparison between 41 Turner patients and a control group of 51 normal adult women revealed significant differences regarding craniofacial size and morphology. The calvarium, maxilla, and mandible were smaller in Turner syndrome patients and the cranial base was shorter and flattened. The maxilla and the mandible were retrognathic and posteriorly inclined in relation to the cranial base. Sagittal jaw relationship and overjet was greater in Turner syndrome. In the craniocervical area seven syndrome patients presented anomalies. Craniofacial morphology did not differ in 45,X cases and Turner patients with other X-chromosome aberrations. It was concluded that the posterior inclination and retrognathism of the maxilla and the mandible in Turner syndrome could be related to the altered shape of the cranial base.
本研究的目的是分析特纳综合征成年患者的颅面形态，并比较45,X核型患者与其他X染色体畸变患者的形态。对41名特纳综合征患者和51名正常成年女性对照组进行比较，结果显示颅面大小和形态存在显著差异。特纳综合征患者的颅骨、上颌骨和下颌骨较小，颅底较短且扁平。上颌骨和下颌骨相对于颅底后缩且向后倾斜。特纳综合征患者的矢状颌关系和覆盖更大。在颅颈区域，7名综合征患者出现异常。45,X病例与其他X染色体畸变的特纳综合征患者的颅面形态没有差异。研究得出结论，特纳综合征中上颌骨和下颌骨的后倾和后缩可能与颅底形状改变有关。
