Holmes C S, Richman L C
J Dev Behav Pediatr. 1985 Dec;6(6):323-6.
Intellectual and reading skills were evaluated and related to disease variables in 42 children with Type I (insulin-dependent) diabetes. A significant interaction revealed lower Wechsler Intelligence Scale for Children-Revised (WISC-R) Performance IQ for children with early disease onset (less than 7 years) and long disease duration (greater than or equal to 5 years). IQ scores were nevertheless in the average range. Although there was no specific pattern of visual spatial impairment, functioning on the Performance subtests was uniformly lower for this group. Slower responding to the timed tasks of the Performance scale may account for generally lower scores. Children with early onset-long duration also evidenced higher rates of reading and memory impairment. These results indicate the importance of ascertaining educational skills in diabetic children before planning diabetic treatment regimens, especially for children with disease of early onset and long duration, who may be especially vulnerable to skill deficits.
对42名I型（胰岛素依赖型）糖尿病儿童的智力和阅读技能进行了评估，并将其与疾病变量相关联。一项显著的交互作用显示，疾病发病早（小于7岁）且病程长（大于或等于5年）的儿童，其韦氏儿童智力量表修订版（WISC-R）操作智商较低。不过，智商得分仍处于平均范围。虽然没有特定的视觉空间损伤模式，但该组在操作分测验上的表现普遍较低。对操作量表的限时任务反应较慢可能是得分普遍较低的原因。发病早且病程长的儿童阅读和记忆障碍发生率也较高。这些结果表明，在制定糖尿病治疗方案之前，确定糖尿病儿童的教育技能非常重要，尤其是对于发病早且病程长的儿童，他们可能特别容易出现技能缺陷。
