加拿大关于更新一般风险个体结直肠癌筛查起始年龄的考量。
Canadian considerations on updating the age of initiation for colorectal cancer screening in individuals at average risk.
作者信息
Skulsky Samuel Lamarre, Al-Sukhni Eisar, Villiard Roselyne, Li Ting, Li Mo Yu, Dang Jerry T
机构信息
From the University of Ottawa, Department of Surgery, The Ottawa Hospital - General Campus, Ottawa, Ont. (Skulsky); the University Health Network, Department of Surgery, Toronto, Ont. (Al-Sukhni); the University of Toronto Faculty of Medicine, Toronto, Ont. (Al-Sukhni); the Centre hospitalier régional de Lanaudière, Department of Surgery, Saint-Charles-Borromée, Que. (Villiard); the Université Laval, Department of Surgery, Québec, Que. (Villiard); the Peterborough Regional Health Centre, Department of Surgery, Peterborough, Ont. (Li); the University of Calgary, Department of Surgery, Calgary, Alta. (Li); the Cleveland Clinic Foundation, Bariatric, Foregut, and Flexible Endoscopic Surgery Digestive Disease Institute, Cleveland, Ohio, USA (Dang)
From the University of Ottawa, Department of Surgery, The Ottawa Hospital - General Campus, Ottawa, Ont. (Skulsky); the University Health Network, Department of Surgery, Toronto, Ont. (Al-Sukhni); the University of Toronto Faculty of Medicine, Toronto, Ont. (Al-Sukhni); the Centre hospitalier régional de Lanaudière, Department of Surgery, Saint-Charles-Borromée, Que. (Villiard); the Université Laval, Department of Surgery, Québec, Que. (Villiard); the Peterborough Regional Health Centre, Department of Surgery, Peterborough, Ont. (Li); the University of Calgary, Department of Surgery, Calgary, Alta. (Li); the Cleveland Clinic Foundation, Bariatric, Foregut, and Flexible Endoscopic Surgery Digestive Disease Institute, Cleveland, Ohio, USA (Dang).
出版信息
Can J Surg. 2025 Aug 8;68(4):E313-E324. doi: 10.1503/cjs.000825. Print 2025 Jul-Aug.
The incidence of early-onset colorectal cancer (CRC), defined as CRC occurring in individuals younger than 50 years, is increasing globally. Emerging evidence suggests that the incidence and prevalence of CRC in individuals aged 45-49 years approach those in individuals aged 50-59 years. To address this concerning trend, many health care systems and clinical specialist societies are advocating for lowering the age of initiation for CRC screening in individuals at average risk to 45 years. The present review, provided by the Canadian Association of General Surgeons Clinical Practice Committee, gives an overview of the current CRC screening guidelines in Canada, the rationale for earlier screening, and the challenges and impact of lowering the screening age to 45 years to health care systems in Canada.
早发性结直肠癌（CRC）定义为发生在50岁以下个体中的结直肠癌，其全球发病率正在上升。新出现的证据表明，45-49岁个体的结直肠癌发病率和患病率接近50-59岁个体。为应对这一令人担忧的趋势，许多医疗保健系统和临床专科协会主张将平均风险个体的CRC筛查起始年龄降至45岁。由加拿大普通外科医生协会临床实践委员会提供的本综述概述了加拿大当前的CRC筛查指南、早期筛查的理由，以及将筛查年龄降至45岁对加拿大医疗保健系统的挑战和影响。
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