Xue Xiaoqin, Zeng Guihua, Li Ting, Xiao Qian, He Lin
Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, 341000, Jiangxi, China.
Dig Dis Sci. 2025 Aug 9. doi: 10.1007/s10620-025-09299-y.
Acute pancreatitis (AP) is a serious and sometimes life-threatening condition that can lead to complications like organ failure and infection. While early mobility has shown benefits in other hospital settings, its role in AP care remains underexplored. This study assessed the impact of a nurse-led early mobilization program on recovery in AP patients.
A randomized controlled trial included 240 patients diagnosed with acute pancreatitis, split equally between an intervention group and a control group. The intervention group received a nurse-led early mobilization plan within 24 h of admission, while the control group followed standard care, with mobilization delayed until clinical stabilization. Primary outcomes included the Barthel Index score for functional recovery, measured at discharge, while secondary outcomes included complications, satisfaction, and readmission rates. Analyses used multivariate regression and propensity score matching.
Patients who received early mobilization had significantly higher Barthel scores (mean = 75.84 vs. 65.5, p < 0.001). Although complication rates were lower in the intervention group (2.1% vs. 4.6%), the difference was not statistically significant (p = 0.121). Patient satisfaction was notably higher in the intervention group (median = 8 vs. 7, p < 0.001). Readmission rates were slightly lower but not significant (0.4% vs. 1.3%, p = 0.313). Propensity score analysis supported these findings.
Nurse-led early mobilization appears to boost functional recovery and satisfaction in AP patients, with no added risks. These findings suggest early mobilization may be a valuable addition to standard AP care, warranting further research.
ChiCTR2000013176.
急性胰腺炎（AP）是一种严重的疾病，有时会危及生命，可导致器官衰竭和感染等并发症。虽然早期活动在其他医院环境中已显示出益处，但其在AP护理中的作用仍未得到充分探索。本研究评估了由护士主导的早期活动计划对AP患者康复的影响。
一项随机对照试验纳入了240例诊断为急性胰腺炎的患者，平均分为干预组和对照组。干预组在入院后24小时内接受由护士主导的早期活动计划，而对照组遵循标准护理，活动延迟至临床稳定。主要结局包括出院时测量的功能恢复的Barthel指数评分，次要结局包括并发症、满意度和再入院率。分析采用多变量回归和倾向得分匹配。
接受早期活动的患者Barthel评分显著更高（平均 = 75.84对65.5，p < 0.001）。虽然干预组的并发症发生率较低（2.1%对4.6%），但差异无统计学意义（p = 0.121）。干预组患者满意度明显更高（中位数 = 8对7，p < 0.001）。再入院率略低但不显著（0.4%对1.3%，p = 0.313）。倾向得分分析支持了这些发现。
由护士主导的早期活动似乎能促进AP患者的功能恢复和满意度，且无额外风险。这些发现表明早期活动可能是标准AP护理中有价值的补充，值得进一步研究。
ChiCTR2000013176。
