Malofsky H, Lopez A L
J Foot Surg. 1985 Nov-Dec;24(6):445-7.
Microfibrillar collagen is described. The method of application and use on the exposed surface of cancellous bone encountered in heel spur surgery, herein defined as a resection of the inferior calcaneal exostosis with plantar fasciotomy, is discussed. Microfibrillar collagen's chief effect on cancellous bone is rapid, dramatic cessation of bone bleeding. It was assessed in terms of its effect on postoperative pain, quantitative subcutaneous hematoma formation, and edema. Although patients initially experienced increased discomfort during the first 24 hr. postoperatively, their edema, subcutaneous hematoma formation, and, more dramatically, need for narcotic analgesics was significantly reduced in the microfibrillar patient group when compared to patients having the same surgical procedures without the microfibrillar collagen intraoperatively. There were no postoperative complications encountered after the use of microfibrillar collagen in any of the 23 cases.
对微纤维胶原进行了描述。讨论了其在跟骨刺手术中遇到的松质骨暴露表面的应用方法及用途，在此将其定义为通过足底筋膜切开术切除跟骨下骨赘。微纤维胶原对松质骨的主要作用是迅速、显著地停止骨出血。对其在术后疼痛、定量皮下血肿形成和水肿方面的效果进行了评估。尽管患者在术后最初24小时内不适感有所增加，但与术中未使用微纤维胶原而进行相同手术的患者相比，微纤维胶原治疗组患者的水肿、皮下血肿形成，更显著的是对麻醉性镇痛药的需求明显减少。在23例使用微纤维胶原的病例中，术后均未出现并发症。
