Beydoun Hind A, Beydoun May A, Hale Lauren, Wallace Robert B, Jung Su Yon, Saquib Nazmus, Szymkowiak Dorota, Derefinko Karen, Zonderman Alan B, Brunner Robert, Tsai Jack
VA National Center on Homelessness Among Veterans, U.S. Department of Veterans Affairs, Washington, DC, USA; Department of Management, Policy, and Community Health, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Laboratory of Epidemiology and Population Sciences, National Institute on Aging Intramural Research Program, Baltimore, MD, USA.
J Affect Disord. 2025 Dec 15;391:120011. doi: 10.1016/j.jad.2025.120011. Epub 2025 Aug 7.
To examine among women ≥65 years: [1] differences in prevalence and incidence of psychiatric disorders, including substance use and mental health disorders, by veteran status; and [2] relationships of individual and neighborhood socioeconomic status (SES) with psychiatric disorders by veteran status.
A total of 42,031 study-eligible women ≥65 years at enrollment (1993-1998) from the Women's Health Initiative (WHI) - including 1512 veterans - were evaluated for approximately 15 years of follow-up through linked WHI-Medicare databases. Multivariable logistic and Cox regression models were constructed for characteristics associated with prevalent and incident psychiatric disorders, respectively.
Psychiatric disorders affected a substantial proportion of women ≥65 years of age, with mood and anxiety disorders being the leading types of disorders. The overall prevalence and incidence rates of psychiatric disorders were 37.3 % and 25.5 per 1000 person-years, respectively. In adjusted models, frequencies of psychiatric disorders did not differ by veteran status. Also, lower education, household income, and neighborhood SES were related to higher frequencies of psychiatric disorders only among women non-veterans, whereas managerial/professional occupations were associated with lower frequencies of psychiatric disorders among women irrespective of their veteran status. However, interactions between veteran status and SES indicators in relation to psychiatric disorders were not statistically significant.
Disparities in psychiatric disorders by individual-level and neighborhood-level SES may be distinct among older women veterans and non-veterans necessitating in-depth investigation.
在65岁及以上女性中研究:[1]退伍军人身份与精神疾病(包括物质使用和心理健康障碍)的患病率和发病率差异;[2]个人及邻里社会经济地位(SES)与退伍军人身份相关的精神疾病之间的关系。
来自女性健康倡议(WHI)(1993 - 1998年入组时年龄≥65岁的符合研究条件的42,031名女性,其中包括1512名退伍军人)通过WHI - 医疗保险关联数据库进行了约15年的随访评估。分别构建了与精神疾病患病率和发病率相关特征的多变量逻辑回归模型和Cox回归模型。
精神疾病影响了很大比例的65岁及以上女性,情绪和焦虑障碍是主要的疾病类型。精神疾病的总体患病率和发病率分别为37.3%和每1000人年25.5例。在调整模型中,精神疾病的发生率不因退伍军人身份而异。此外,较低的教育程度、家庭收入和邻里SES仅在非退伍军人女性中与较高的精神疾病发生率相关,而管理/专业职业与无论退伍军人身份的女性中较低的精神疾病发生率相关。然而,退伍军人身份与SES指标在精神疾病方面的相互作用无统计学意义。
老年退伍军人女性和非退伍军人女性在个人层面和邻里层面SES导致的精神疾病差异可能不同,需要深入调查。