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[钬激光前列腺尖部ω形预横断并保留膀胱颈可改善良性前列腺增生症患者经尿道钬激光前列腺剜除术后的尿控和性功能]

[Holmium laser ω-shaped pre-transection of prostate apex with preservation of the bladder neck improves urinary continence and sexual function in BPH patients after HoLEP].

作者信息

Zhang Bin-Bin, DU Ling-Ling, Jia Jun-Qi, Yan Wen-Shuai, Gao Ji-Xue, Wang Feng, Qiang Ya-Yong

机构信息

Department of Urology, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi 716000, China;.

Department of Cardiology, Yan'an People's Hospital, Yan'an, Shaanxi 716000, China.

出版信息

Zhonghua Nan Ke Xue. 2024 Dec;30(12):1091-1097.

Abstract

OBJECTIVE

To investigate the effect of holmium laser ω-shaped pre-transection of the prostate apex (PTPA) with preservation of the bladder neck on the urinary continence and sexual function of the patients with BPH after transurethral holmium laser enucleation of the prostate (HoLEP).

METHODS

This retrospective study included 165 cases of BPH undergoing holmium laser ω-shaped PTPA with preservation of the bladder neck following HoLEP from January 2018 to January 2023. We recorded and compared the baseline, perioperative and 12-month follow-up data on the patients, and evaluated their urination function using IPSS, maximum urinary flow rate (Qmax), postvoid residual urine volume (PVR), and quality of life (QOL) scores. For those who had had sexual activity and normal ejaculation before surgery, we further assessed their erectile and ejaculatory functions postoperatively.

RESULTS

The mean surgical time was (70.35±12.27) min, the intraoperative blood loss (60.12±19.54) ml, and the weight of the excised gland (56.37±13.71) g. The hospital stay and postoperative catheter-indwelling time averaged (5.13±2.34) and (3.21±1.37) d, respectively. Significant improvements were observed in IPSS, QOL, PVR and Qmax at 3, 6 and 12 months after surgery compared with the baseline (P<0.05), which all remained stable throughout the follow-up period. At 3 months after surgery, stress urinary incontinence was found in 10.91% of the patients, and all but 1 case (0.6%) recovered within 12 months. There were no significant changes in the IIEF-5 and Erectile Hardness Scale (EHS) scores postoperatively (P>0.05). Retrograde ejaculation occurred in 19 (11.52%) of the patients, but none experienced painful ejaculation after surgery.

CONCLUSION

Holmium laser ω-shaped PTPA with preservation of the bladder neck is safe and effective for the treatment of BPH, which can effectively improve the urinary continence and protect the sexual function of the patient.

摘要

目的

探讨钬激光前列腺尖部ω形预切开术(PTPA)并保留膀胱颈对经尿道钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)患者尿失禁及性功能的影响。

方法

本回顾性研究纳入了2018年1月至2023年1月期间165例行HoLEP后行钬激光前列腺尖部ω形预切开术并保留膀胱颈的BPH患者。我们记录并比较了患者的基线、围手术期及12个月随访数据,使用国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、残余尿量(PVR)及生活质量(QOL)评分评估其排尿功能。对于术前有性活动且射精正常的患者,我们进一步评估其术后勃起及射精功能。

结果

平均手术时间为(70.35±12.27)分钟,术中出血量为(60.12±19.54)毫升,切除腺体重量为(56.37±13.71)克。住院时间和术后留置导尿管时间平均分别为(5.13±2.34)天和(3.21±1.37)天。与基线相比,术后3、6和12个月时IPSS、QOL、PVR和Qmax均有显著改善(P<0.05),且在整个随访期间均保持稳定。术后3个月时,10.91%的患者出现压力性尿失禁,除1例(0.6%)外,所有患者在12个月内均恢复。术后国际勃起功能指数-5(IIEF-5)和勃起硬度评分(EHS)无显著变化(P>0.05)。19例(11.52%)患者发生逆行射精,但术后均无射精疼痛。

结论

钬激光前列腺尖部ω形预切开术并保留膀胱颈治疗BPH安全有效,可有效改善患者尿失禁并保护其性功能。

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