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吲哚菁绿在减重与代谢手术中的应用安全性

Safety of indocyanine green use in bariatric and metabolic surgery.

作者信息

Wityk Mateusz, Bobowicz Maciej, Dowgiałło-Gornowicz Natalia

机构信息

Department of General and Oncological Surgery, Regional Health Centre, Lubin, Poland.

Department of Radiology, Medical University of Gdansk, Gdańsk, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2025 Jul 4;20(2):215-219. doi: 10.20452/wiitm.2025.17964. eCollection 2025 Jul 8.

Abstract

INTRODUCTION

Intraoperative indocyanine green (ICG) is increasingly used in surgery. In metabolic and bariatric surgery, it allows visualization of the tissues and blood supply to anastomoses in real time.

AIM

The objective of this prospective cohort study was to evaluate the safety and efficacy of ICG usage in metabolic and bariatric surgery.

MATERIALS AND METHODS

The study was conducted from July 2022 to December 2023. A total of 171 metabolic and bariatric procedures with ICG perfusion tests were performed, comprising 93 sleeve gastrectomies, 17 one-anastomosis gastric bypasses, 51 Roux-en-Y gastric bypasses, 7 primary single anastomosis duodeno-ileal bypasses with sleeve gastrectomies, and 3 redo surgeries.

RESULTS

Out of 171 patients included in the study, 143 (83.6%) were women. Mean (SD) age of the participants was 41.8 (9.7) years, and mean (SD) body mass index was 44.6 (6.3) kg/m. Mean (SD) operation time was 92.9 (47.7) minutes, and mean (SD) length of hospital stay was 2.1 (0.8) days. Surgical complications occurred in 4 patients (2.3%). No local or general adverse symptoms or complications, including allergic reactions, were observed after intravenous administration of ICG. The patients' allergies did not influence adverse events related to the administration of the dye.

CONCLUSIONS

The use of intraoperative ICG in metabolic and bariatric surgery is safe, and adverse events and dye-related complications are very rare.

摘要

引言

术中吲哚菁绿(ICG)在手术中的应用越来越广泛。在代谢和减重手术中,它能够实时显示组织情况以及吻合口的血供。

目的

这项前瞻性队列研究的目的是评估ICG在代谢和减重手术中的安全性和有效性。

材料与方法

该研究于2022年7月至2023年12月进行。共进行了171例采用ICG灌注试验的代谢和减重手术,包括93例袖状胃切除术、17例单吻合口胃旁路术、51例Roux-en-Y胃旁路术、7例袖状胃切除术联合一期单吻合十二指肠空肠旁路术以及3例再次手术。

结果

纳入研究的171例患者中,143例(83.6%)为女性。参与者的平均(标准差)年龄为41.8(9.7)岁,平均(标准差)体重指数为44.6(6.3)kg/m²。平均(标准差)手术时间为92.9(47.7)分钟,平均(标准差)住院时间为2.1(0.8)天。4例患者(2.3%)发生手术并发症。静脉注射ICG后未观察到局部或全身不良反应或并发症,包括过敏反应。患者的过敏情况未影响与染料给药相关的不良事件。

结论

术中使用ICG在代谢和减重手术中是安全的,不良事件和与染料相关的并发症非常罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f900/12329663/d29acdf37b43/vomt-20-2-17964-g1.jpg

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