Li Ni, Chen Xi
Department of Cardiology, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.
Department of Critical Care Medicine, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.
Front Physiol. 2025 Jul 25;16:1597416. doi: 10.3389/fphys.2025.1597416. eCollection 2025.
Percutaneous coronary intervention for myocardial infarction can cause reperfusion injury with both physical and psychological impacts on patients. This study aims to assess how evidence-based nursing affects psychological state and myocardial injury in reperfusion injury in patients with myocardial infarction following percutaneous coronary intervention.
Ninety patients with myocardial infarction who underwent percutaneous coronary intervention and were confirmed to have postoperative reperfusion injury were randomly divided into a control group that received conventional care or an intervention group that received evidence-based nursing intervention. The levels of cardiac function indicators (left ventricular ejection fraction and left ventricular end-diastolic diameter), myocardial injury markers (N-terminal pro-b-type natriuretic peptide and cardiac troponin I), psychological status (Self-Rating Anxiety Scale and Self-Rating Depression Scale scores), the incidence of complications, mortality rate, and satisfaction with nursing care were compared before and after the intervention.
Compared to pre-intervention, after the intervention, both groups showed reductions in left ventricular end-diastolic diameter, N-terminal pro-b-type natriuretic peptide, cardiac troponin I levels, Self-Rating Anxiety Scale and Self-Rating Depression Scale scores, with an increase in left ventricular ejection fraction. The intervention group demonstrated superior outcomes in all these metrics compared to the control group, with lower rates of complications and mortality, and higher satisfaction levels.
Implementing evidence-based nursing in patients with myocardial infarction undergoing percutaneous coronary intervention for reperfusion injury can improve cardiac function, alleviate myocardial injury and psychological status, reduce the incidence of complications, and enhance patient satisfaction.
经皮冠状动脉介入治疗心肌梗死可导致再灌注损伤，对患者产生生理和心理影响。本研究旨在评估循证护理对经皮冠状动脉介入治疗后心肌梗死患者再灌注损伤时心理状态和心肌损伤的影响。
将90例接受经皮冠状动脉介入治疗且确诊术后存在再灌注损伤的心肌梗死患者随机分为接受常规护理的对照组或接受循证护理干预的干预组。比较干预前后两组的心功能指标（左心室射血分数和左心室舒张末期内径）、心肌损伤标志物（N末端B型利钠肽原和心肌肌钙蛋白I）、心理状态（焦虑自评量表和抑郁自评量表评分）、并发症发生率、死亡率及护理满意度。
与干预前相比，干预后两组患者的左心室舒张末期内径、N末端B型利钠肽原、心肌肌钙蛋白I水平、焦虑自评量表和抑郁自评量表评分均降低，左心室射血分数升高。干预组在所有这些指标上的结果均优于对照组，并发症和死亡率更低，满意度更高。
对接受经皮冠状动脉介入治疗以处理再灌注损伤的心肌梗死患者实施循证护理可改善心功能，减轻心肌损伤和心理状态，降低并发症发生率，并提高患者满意度。
