Peng Min'an, Li Jie, Kuang Linhua, Guo Jugen, Liu Shantao, Ye Changqing
Department of Cardiology, The Ji'an Central People's Hospital, Ji'an, 343000, Jiangxi, P.R. China.
Department of geriatric intensive Care Medicine, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 519041, Guangdong, P.R. China.
J Cardiothorac Surg. 2025 Apr 12;20(1):192. doi: 10.1186/s13019-025-03427-5.
Psychological factors are closely correlated with coronary heart disease, and gender discrepancies occurs in mental health after percutaneous coronary intervention (PCI) for acute coronary syndrome patients (ACS) are worth studying.
This study collected data from patients aged ≥ 60 diagnosed with ACS who underwent PCI treatment within one week of admission to the Cardiovascular Department of Ji'an Central People's Hospital between June 2021 and December 2022. The study group consisted of 113 female patients, whereas the control group consisted of 121 male patients. Baseline patient data, demography, and laboratory test results were collected. Anxiety and depression were assessed using the Self-rating anxiety scale (SAS) and Self-rating depression scale (SDS) before PCI and at 1, 4, and 12 weeks post-procedure. Descriptive data are presented as x̄±s. Group comparisons for continuous variables were conducted using t-tests, while categorical data were analyzed using chi-square tests. Multiple group comparisons were conducted using analysis of variance.
There were no statistically significant disparities observed in baseline characteristics between these two groups. The assessment of SAS and SDS scores exhibited no statistically significant difference between the two groups before PCI; however, after the procedure, elderly female ACS patients demonstrated notably elevated SAS and SDS scores when contrasted with their elderly male ACS counterparts. Both cohorts manifested their highest SAS and SDS scores before PCI, with a gradual reduction in these scores after the procedure. Elderly female ACS patients experienced a statistically significant reduction in SAS and SDS scores at both 4- and 12 weeks post-PCI compared to their pre-PCI scores.
Taken together, elderly female ACS patients undergoing PCI are more susceptible to the manifestation of anxiety and depression symptoms compared to their elderly male counterparts.
心理因素与冠心病密切相关,急性冠状动脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)后心理健康存在性别差异,值得研究。
本研究收集了2021年6月至2022年12月期间在吉安市中心人民医院心血管内科住院一周内接受PCI治疗的年龄≥60岁的ACS患者的数据。研究组由113名女性患者组成,对照组由121名男性患者组成。收集患者的基线数据、人口统计学和实验室检查结果。在PCI术前以及术后1周、4周和12周,使用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估焦虑和抑郁情况。描述性数据以x̄±s表示。连续变量的组间比较采用t检验,分类数据采用卡方检验进行分析。多组比较采用方差分析。
两组在基线特征方面未观察到统计学上的显著差异。PCI术前两组的SAS和SDS评分评估无统计学显著差异;然而,术后,老年女性ACS患者与老年男性ACS患者相比,SAS和SDS评分显著升高。两组在PCI术前SAS和SDS评分均最高,术后这些评分逐渐降低。与PCI术前评分相比,老年女性ACS患者在PCI术后4周和12周时SAS和SDS评分有统计学显著降低。
总体而言,接受PCI的老年女性ACS患者比老年男性ACS患者更容易出现焦虑和抑郁症状。