Tomoda Yoshitaka, Wasai Naoki, Ukai Kohei, Tanaka Hiroaki, Kitaura Satoshi
General Internal Medicine, Itabashi Chuo Medical Center, Itabashi, JPN.
Infectious Disease, Itabashi Chuo Medical Center, Itabashi, JPN.
Cureus. 2025 Jul 10;17(7):e87700. doi: 10.7759/cureus.87700. eCollection 2025 Jul.
Lemierre's syndrome is classically characterized by bacteremia with jugular venous thrombophlebitis, typically affecting young adults following oropharyngeal infections. We report an unusual case of disseminated infection in a 53-year-old man who presented without pharyngitis or jugular venous thrombophlebitis, instead manifesting with septic pulmonary emboli, bilateral empyema, liver abscess, and portal vein thrombophlebitis. This case highlights the importance of recognizing atypical presentations of invasive infections, which are associated with higher mortality rates compared to classic Lemierre's syndrome. Early diagnosis and aggressive multimodal treatment led to the successful management of this complex case.
勒米尔综合征的典型特征是伴有颈静脉血栓性静脉炎的菌血症，通常影响口咽感染后的年轻人。我们报告了一例53岁男性的罕见播散性感染病例，该患者没有咽炎或颈静脉血栓性静脉炎，而是表现为脓毒性肺栓塞、双侧脓胸、肝脓肿和门静脉血栓性静脉炎。该病例强调了认识侵袭性感染非典型表现的重要性，与经典的勒米尔综合征相比，这些非典型表现与更高的死亡率相关。早期诊断和积极的多模式治疗成功地处理了这一复杂病例。
