Kelly Quyen, Fogel Joshua, Harrison Shauna, Bryson Lennox
Department of Obstetrics & Gynecology, Nassau University Medical Center, East Meadow, NY, USA (QK, JF, SH, LB).
Department of Management, Marketing and Entrepreneurship, Brooklyn College of the City University of New York, Brooklyn, NY, USA (JF).
Am J Lifestyle Med. 2025 Aug 5:15598276251365131. doi: 10.1177/15598276251365131.
To investigate the association of dietary and psychological health variables with infertility. A cross-sectional survey was administered to non-pregnant women aged 18-34 years. Data were collected on dietary topics (practices, formal diets, psychological beliefs) and psychological health (depression, anxiety, stress). Covariates included demographics and medical history. Infertility was defined as self-reported clinical diagnosis or lack of conception for more than one year with at least 18 months elapsed time since the last birth. Multivariate logistic regression was used to identify independent predictors of infertility. Among 398 participants, 149 (37.4%) met the criteria for infertility. In multivariate analysis, the belief of being overweight (OR 2.59; 95% CI: 1.40-4.81) was significantly associated with infertility, whereas other dietary variables were not. Moderate-to-severe anxiety (OR 2.01; 95% CI: 1.08-3.72) and high perceived stress (OR 1.86; 95% CI: 1.07-3.23) were also significantly associated with infertility, while depression showed no significant association. We recommend that clinicians adopt a comprehensive approach to early infertility evaluation that includes not only formal screening for psychological health status, but also psychological aspects of diet. Such early identification and lifestyle interventions in these domains may improve reproductive outcomes and enhance patient care.
为研究饮食和心理健康变量与不孕症之间的关联。对18 - 34岁的未孕女性进行了一项横断面调查。收集了有关饮食主题(习惯、正规饮食、心理信念)和心理健康(抑郁、焦虑、压力)的数据。协变量包括人口统计学和病史。不孕症定义为自我报告的临床诊断或自上次分娩后至少经过18个月仍未受孕超过一年。采用多因素逻辑回归来确定不孕症的独立预测因素。在398名参与者中,149名(37.4%)符合不孕症标准。在多因素分析中,超重信念(比值比2.59;95%置信区间:1.40 - 4.81)与不孕症显著相关,而其他饮食变量则不然。中度至重度焦虑(比值比2.01;95%置信区间:1.08 - 3.72)和高感知压力(比值比1.86;95%置信区间:1.07 - 3.23)也与不孕症显著相关,而抑郁则无显著关联。我们建议临床医生采用一种全面的方法进行早期不孕症评估,不仅包括对心理健康状况的正规筛查,还包括饮食的心理方面。在这些领域进行早期识别和生活方式干预可能会改善生殖结局并提高患者护理质量。