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韩国肝细胞癌经动脉放射性栓塞治疗：当前临床实践、设施要求及患者选择

Transarterial Radioembolization for Hepatocellular Carcinoma in Korea: Current Clinical Practices, Facility Requirements, and Patient Selection.

作者信息

Hyun Dongho

出版信息

J Korean Soc Radiol. 2025 Jul;86(4):447-456. doi: 10.3348/jksr.2025.0049. Epub 2025 Jul 25.

DOI:10.3348/jksr.2025.0049
PMID:40787306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12328919/
Abstract

Before initiating Yttrium-90 (Y) radioembolization, both the interventional radiology and nuclear medicine departments must prepare facilities for radionuclide handling, implement appropriate radiation protection and monitoring measures, and ensure that all medical personnel possess the required government-issued certification. According to current guidelines, transarterial radioembolization is recommended as an alternative treatment option for patients with a single hepatocellular carcinoma measuring ≤8 cm and classified as stage I, II, or III according to the modified Union for International Cancer Control staging system. However, these indications may be adjusted based on the institution's medical clinical setting and resources. Given the potential for irreversible tissue damage from Y, treatment efficacy and safety must be assessed through planning angiography and either planar imaging or SPECT-CT using Tc-macroaggregated albumin.

摘要

在开始钇-90（Y）放射性栓塞治疗之前，介入放射科和核医学科都必须准备好处理放射性核素的设施，实施适当的辐射防护和监测措施，并确保所有医务人员持有政府颁发的所需证书。根据现行指南，对于单个肝细胞癌直径≤8 cm且根据国际癌症控制联盟改良分期系统分类为I期、II期或III期的患者，推荐经动脉放射性栓塞作为一种替代治疗选择。然而，这些适应症可能会根据机构的医疗临床情况和资源进行调整。鉴于Y可能造成不可逆的组织损伤，必须通过计划血管造影以及使用锝标记的大颗粒白蛋白进行平面成像或SPECT-CT来评估治疗效果和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/57a34be690a5/jksr-86-447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/e04ae56a747e/jksr-86-447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/e7b8d31a7594/jksr-86-447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/9398b5972137/jksr-86-447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/87ba02b25b81/jksr-86-447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/57a34be690a5/jksr-86-447-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/e04ae56a747e/jksr-86-447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/e7b8d31a7594/jksr-86-447-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/9398b5972137/jksr-86-447-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/87ba02b25b81/jksr-86-447-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ce/12328919/57a34be690a5/jksr-86-447-g005.jpg

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本文引用的文献

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J Vasc Interv Radiol. 2025 Sep;36(9):1427-1435.e3. doi: 10.1016/j.jvir.2025.05.027. Epub 2025 May 29.
2
Yttrium-90 Radioembolization Dosimetry: Dose Considerations, Optimization, and Tips.钇-90放射性栓塞剂量学：剂量考量、优化及小贴士
Semin Intervent Radiol. 2024 Mar 14;41(1):63-78. doi: 10.1055/s-0044-1779715. eCollection 2024 Feb.
3
Transarterial Radioembolization: Overview of Radioembolic Devices.
经动脉放射性栓塞：放射性栓塞装置概述
Semin Intervent Radiol. 2023 Nov 2;40(5):461-466. doi: 10.1055/s-0043-1772814. eCollection 2023 Oct.
4
2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma.《2022年韩国肝脏癌协会-韩国国立癌症中心肝细胞癌管理实践指南》
J Liver Cancer. 2023 Mar;23(1):1-120. doi: 10.17998/jlc.2022.11.07. Epub 2022 Dec 9.
5
Clinical, dosimetric, and reporting considerations for Y-90 glass microspheres in hepatocellular carcinoma: updated 2022 recommendations from an international multidisciplinary working group.用于肝细胞癌的 Y-90 玻璃微球的临床、剂量学和报告考虑因素：国际多学科工作组的 2022 年更新建议。
Eur J Nucl Med Mol Imaging. 2023 Jan;50(2):328-343. doi: 10.1007/s00259-022-05956-w. Epub 2022 Sep 17.
6
Radiation segmentectomy for curative intent of unresectable very early to early stage hepatocellular carcinoma (RASER): a single-centre, single-arm study.根治性意向不可切除的非常早期到早期肝细胞癌的放射段切除术（RASER）：单中心、单臂研究。
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BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update.BCLC 策略用于预后预测和治疗推荐：2022 年更新版。
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Yttrium-90 Radioembolization for the Treatment of Solitary, Unresectable HCC: The LEGACY Study.钇-90 放射性栓塞治疗不可切除单发 HCC：LEGACY 研究。
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