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Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a model-based cost-effectiveness analysis of a pragmatic, cluster-randomised trial in seven low-income and middle-income countries.常规腹部伤口缝合时更换无菌手套和器械以预防手术部位感染(ChEETAh):在七个低收入和中等收入国家进行的一项实用、整群随机试验的基于模型的成本效益分析。
Lancet Glob Health. 2024 Feb;12(2):e235-e242. doi: 10.1016/S2214-109X(23)00538-7.
2
Global Incidence of Surgical Site Infection Among Patients: Systematic Review and Meta-Analysis.全球患者手术部位感染发生率:系统评价和荟萃分析。
Inquiry. 2023 Jan-Dec;60:469580231162549. doi: 10.1177/00469580231162549.
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Cost-effectiveness analysis of an active 30-day surgical site infection surveillance at a tertiary hospital in Ghana: evidence from HAI-Ghana study.加纳一家三级医院主动开展术后 30 天手术部位感染监测的成本效益分析:来自 HAI-Ghana 研究的证据。
BMJ Open. 2022 Jan 3;12(1):e057468. doi: 10.1136/bmjopen-2021-057468.
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Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial.在中低收入国家减少手术部位感染(隼鹰):一项实用的、多中心的、分层的、随机对照试验。
Lancet. 2021 Nov 6;398(10312):1687-1699. doi: 10.1016/S0140-6736(21)01548-8. Epub 2021 Oct 25.
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Incidence, risk factors and outcomes of surgical site infections among patients admitted to Jimma Medical Center, South West Ethiopia: Prospective cohort study.埃塞俄比亚西南部吉马医疗中心收治患者手术部位感染的发生率、危险因素及结局:前瞻性队列研究
Ann Med Surg (Lond). 2021 Mar 29;65:102247. doi: 10.1016/j.amsu.2021.102247. eCollection 2021 May.
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Global burden of postoperative death.术后死亡的全球负担。
Lancet. 2019 Feb 2;393(10170):401. doi: 10.1016/S0140-6736(18)33139-8.
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Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study.高收入、中等收入和低收入国家胃肠道手术后手术部位感染:一项前瞻性、国际、多中心队列研究。
Lancet Infect Dis. 2018 May;18(5):516-525. doi: 10.1016/S1473-3099(18)30101-4. Epub 2018 Feb 13.

减轻低收入和中等收入国家手术部位感染的负担:挑战与建议

Reducing the burden of surgical site infections in low and middle-income countries: challenges and recommendations.

作者信息

Tahir Muhammad Fawad, Mughal Sanila, Nadeem Amna, Khan Maimoona, Hannat Ramish, Jaber Amin Mohammed Hammad

机构信息

HBS Medical and Dental College, Islamabad, Pakistan.

Dow University of Health Sciences, Karachi, Pakistan.

出版信息

Ann Med Surg (Lond). 2025 Jun 13;87(8):5335-5337. doi: 10.1097/MS9.0000000000003473. eCollection 2025 Aug.

DOI:10.1097/MS9.0000000000003473
PMID:40787548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12333842/
Abstract

Surgical site infections (SSIs) are a significant and growing challenge in surgical care, particularly in low- and middle-income countries (LMICs), where limited resources and inadequate infection control amplify their impact. Affecting up to 25% of surgical patients in some regions, SSIs lead to prolonged hospital stays, increased healthcare costs, and substantial patient suffering. Multidrug-resistant pathogens and inadequate adherence to global guidelines exacerbate the issue, highlighting the need for tailored interventions. Innovative approaches, such as active surveillance programs, routine changes in surgical practices, and enhanced patient education, have shown promise in reducing SSI rates. By prioritizing infection prevention strategies, resource optimization, and collaborative efforts between healthcare providers and policymakers, LMICs can significantly improve surgical outcomes and reduce the burden of SSIs.

摘要

手术部位感染(SSIs)是外科护理中一项重大且日益严峻的挑战,在低收入和中等收入国家(LMICs)尤为如此,这些国家资源有限且感染控制不足,加剧了其影响。在某些地区,手术部位感染影响多达25%的手术患者,导致住院时间延长、医疗费用增加以及患者承受巨大痛苦。多重耐药病原体和对全球指南的依从性不足使问题更加严重,凸显了采取针对性干预措施的必要性。诸如主动监测项目、手术操作常规改变以及加强患者教育等创新方法,在降低手术部位感染率方面已显示出成效。通过优先考虑感染预防策略、资源优化以及医疗服务提供者与政策制定者之间的协作努力,低收入和中等收入国家能够显著改善手术效果并减轻手术部位感染的负担。