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温盐水浴和温水浴对类风湿关节炎患者疼痛、疲劳、睡眠质量及功能能力的影响:一项随机对照研究。

The effect of warm saltwater and warm water baths on pain, fatigue, sleep quality, and functional capacity in patients with rheumatoid arthritis: a randomized controlled study.

作者信息

Aktaş Okşan, Dönmez Ayşe Arikan, Kapucu Sevgisun, Çinar Muhammet

机构信息

Faculty of Nursing, Department of Medical Nursing, Hacettepe University, Ankara, Türkiye, 06100, Turkey.

Gülhane Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, University of Health Sciences, Ankara, Turkey.

出版信息

BMC Complement Med Ther. 2025 Aug 12;25(1):302. doi: 10.1186/s12906-025-05050-2.

Abstract

BACKGROUND

Pain, fatigue, poor sleep quality and functional capacity are the most common symptoms in patients with rheumatoid arthritis. Complementary and integrative methods to be applied by nurses can be an essential strategy in successfully managing these symptoms. The purpose of this study was to examine the effects of warm salt water and warm water baths applied to the hands and feet on pain, fatigue, sleep quality and functional capacity in patients with rheumatoid arthritis.

METHODS

This three-arm and prospective randomized controlled study fifty-four patients were randomly assigned to three groups (warm salt water: 18; warm water: 18; control: 18). Data were collected using the Visual Analog Scale, Bristol Rheumatoid Arthritis Fatigue Multidimensional Questionnaire, Disease Activity Score 28, Pittsburgh Sleep Quality Index, and Health Assessment Questionnaire. The intervention groups received warm saltwater or warm water hand-foot baths for six weeks. In all three groups, the measurements were taken at the beginning of the study and at the end of the last bathing sessions. Data were analyzed with chi-square test, one-way ANOVA, paired sample t-test, and two-way mixed ANOVA with Bonferroni's test.

RESULTS

Two-way mixed ANOVA revealed significant Group × Time interactions for pain (F = 9.736, p < 0.001, η² = 0.249), fatigue (F = 4.323, p = 0.013, η² = 0.158), and fatigue-related quality of life (F = 3.350, p = 0.043, η² = 0.116). Bonferroni post-hoc analyses indicated that both interventions (warm salt water and warm water) led to significant improvements in pain, fatigue, and sleep quality scores compared to the control group (p < 0.05), Notably, the most significant improvement in pain was observed in the warm saltwater group, while the most pronounced reductions in fatigue and fatigue-related quality of life were observed in the warm water group (p < 0.05). Although significant within-group improvements were observed in both intervention groups for sleep quality and only in the warm saltwater group for functional capacity (p < 0.05), no significant Group × Time interactions were found for either outcome (p > 0.05).

CONCLUSIONS

The findings of this study confirmed that warm saltwater and warm water baths applied to the hands and feet improved pain, fatigue, and sleep quality in patients with rheumatoid arthritis. Additionally, warm saltwater baths significantly improved functional capacity. These interventions may serve as safe, accessible, and effective complementary methods for symptom management.

REGISTRATION

Retrospectively registered with the ClinicalTrials.gov (Ref. No: NCT05888220). (Registration Date: 24 May 2023).

摘要

背景

疼痛、疲劳、睡眠质量差和功能能力是类风湿性关节炎患者最常见的症状。护士应用的补充和综合方法可能是成功管理这些症状的关键策略。本研究的目的是检验对手脚进行温盐水浴和温水浴对类风湿性关节炎患者的疼痛、疲劳、睡眠质量和功能能力的影响。

方法

这项三臂前瞻性随机对照研究将54名患者随机分为三组(温盐水组:18名;温水组:18名;对照组:18名)。使用视觉模拟量表、布里斯托尔类风湿性关节炎疲劳多维问卷、疾病活动评分28、匹兹堡睡眠质量指数和健康评估问卷收集数据。干预组接受温盐水或温水手足浴六周。在所有三组中,在研究开始时和最后一次洗浴结束时进行测量。数据采用卡方检验、单因素方差分析、配对样本t检验和带有邦费罗尼检验的双向混合方差分析进行分析。

结果

双向混合方差分析显示,在疼痛(F = 9.736,p < 0.001,η² = 0.249)、疲劳(F = 4.323,p = 0.013,η² = 0.158)和与疲劳相关的生活质量(F = 3.350,p = 0.043,η² = 0.116)方面存在显著的组×时间交互作用。邦费罗尼事后分析表明,与对照组相比,两种干预措施(温盐水和温水)均使疼痛、疲劳和睡眠质量评分有显著改善(p < 0.05)。值得注意的是,温盐水组疼痛改善最为显著,而温水组疲劳及与疲劳相关的生活质量下降最为明显(p < 0.05)。虽然两个干预组在睡眠质量方面均有显著的组内改善,且仅温盐水组在功能能力方面有改善(p < 0.05),但在这两个结果中均未发现显著的组×时间交互作用(p > 0.05)。

结论

本研究结果证实,对手脚进行温盐水浴和温水浴可改善类风湿性关节炎患者的疼痛、疲劳和睡眠质量。此外,温盐水浴显著改善了功能能力。这些干预措施可能是用于症状管理的安全、便捷且有效的补充方法。

注册情况

在ClinicalTrials.gov上进行回顾性注册(注册号:NCT05888220)。(注册日期:2023年5月24日)

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