Lu Xiaomei, He Jing, Ren Liansheng, Yang Rong, Liu Shuhuan, Bai Jingying, Tang Yueqiu, Zeng Yi, Wang Yunmin, Zhang Wei, Zhu Dan
Department of Endocrine Nephrology, 363 Hospital, Chengdu, Sichuan, China.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, National Health Commission & Education Bureau of Heilongjiang Province, Key Laboratory of Etiology and Epidemiology, Harbin Medical University, Center for Chronic Disease Prevention and Control, Harbin Medical University, Harbin, China.
Front Immunol. 2025 Jul 28;16:1627179. doi: 10.3389/fimmu.2025.1627179. eCollection 2025.
We report here a case of allergic eczematoid dermatitis related to hemodialysis access. The patient was initially suspected to have puncture needle allergies or dialyzer reactions until the patient develops a similar response after switching from an arteriovenous fistula (AVF) to a tunneled cuffed catheter (TCC) for dialysis. Thereby, we highly suspected that the allergen was the iodine-containing disinfectant used prior to dialysis, and the patient was ultimately diagnosed with iodine-containing disinfectant allergy. The patient's dermatitis improved remarkably after switching to alcohol disinfection as well as taking oral steroids. Early identification and diagnosis of allergic reactions at the vascular access site can avoid contacting with allergens, accordingly prevent complications like infection and loss of precious vascular accesses in these patients.
我们在此报告一例与血液透析通路相关的过敏性湿疹样皮炎病例。该患者最初被怀疑有穿刺针过敏或透析器反应，直到在从动静脉内瘘（AVF）转换为带隧道带 cuff 的导管（TCC）进行透析后出现类似反应。因此，我们高度怀疑过敏原是透析前使用的含碘消毒剂，该患者最终被诊断为对含碘消毒剂过敏。在改用酒精消毒以及口服类固醇药物后，患者的皮炎显著改善。早期识别和诊断血管通路部位的过敏反应可以避免接触过敏原，从而预防这些患者出现感染和宝贵的血管通路丧失等并发症。
