Englisch Colya N, Wakili Philip, Englisch Clara E, Boden Karl T, Rickmann Annekatrin, Szurman Peter, Messias André
Eye Clinic Sulzbach, Knappschaft Hospitals Saar, Sulzbach/Saar, 66280, Germany.
Department of Experimental Ophthalmology, Saarland University, Homburg/Saar, 66421, Germany.
Am J Ophthalmol Case Rep. 2025 Jul 23;39:102399. doi: 10.1016/j.ajoc.2025.102399. eCollection 2025 Sep.
To report a case of combined Descemet membrane endothelial keratoplasty (DMEK) and secondary sulcus hydrophobic intraocular lens (IOL) implantation for hyperopic correction in a pseudophakic eye with Fuchs' endothelial corneal dystrophy.
A 74-year-old woman with Fuchs' dystrophy and a history of phacoemulsification with a hydrophilic IOL in her left eye (refraction: +5.25 D/-1.00 D × 68°; best corrected visual acuity [BCVA]: 20/40) underwent a preparatory yttrium aluminum garnet (YAG) iridotomy followed by implantation of a hydrophobic add-on +8 D IOL in the ciliary sulcus through a 2.4 mm incision. DMEK was performed using a 90 % fill of 10 % sulfur hexafluoride (SF). Two months after surgery, refraction improved to -0.25 D/-1.75 D × 62° (BCVA: 20/25), with restored corneal clarity and an endothelial cell density of 1920 cells/mm. At 10 months, refraction was +0.75 D/-1.25 D × 54°, and BCVA further improved to 20/20, with an endothelial density of 1778 cells/mm and normalized corneal thickness. No IOL opacification was observed.
This case indicates that combining DMEK with secondary sulcus hydrophobic IOL implantation can effectively correct hyperopia in pseudophakic eyes with Fuchs' dystrophy.
报告一例在患有富克斯内皮角膜营养不良的假晶状体眼中,联合施行Descemet膜内皮角膜移植术(DMEK)和二期睫状沟疏水人工晶状体(IOL)植入术以矫正远视的病例。
一名74岁患有富克斯营养不良且左眼有超声乳化及亲水IOL植入史的女性(验光:+5.25 D/-1.00 D×68°;最佳矫正视力[BCVA]:20/40),先行钇铝石榴石(YAG)虹膜切开术,然后通过2.4 mm切口在睫状沟植入一枚疏水附加+8 D IOL。使用10%六氟化硫(SF)90%填充量进行DMEK手术。术后2个月,验光结果改善为-0.25 D/-1.75 D×62°(BCVA:20/25),角膜清晰度恢复,内皮细胞密度为1920个/mm²。10个月时,验光结果为+0.75 D/-1.25 D×54°,BCVA进一步提高至20/20,内皮密度为1778个/mm²,角膜厚度正常。未观察到IOL混浊。
该病例表明,DMEK与二期睫状沟疏水IOL植入术联合应用可有效矫正患有富克斯营养不良的假晶状体眼中的远视。