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居住在希腊的难民和移民中周围神经病变、糖尿病足的患病率及血糖控制水平

Prevalence of peripheral neuropathy, diabetic foot and level of glycemic control in refugees and migrants residing in Greece.

作者信息

Solomos Zisimangelos, Pappa Eftychia, Tentolouris Nikolaos

机构信息

International Organization for Migration, 6 Dodekanisou str, 17456 Athens, Greece.

Department of Operative Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 2 Thivon str, 115 27 Athens, Greece.

出版信息

J Migr Health. 2025 Jul 25;12:100345. doi: 10.1016/j.jmh.2025.100345. eCollection 2025.

Abstract

INTRODUCTION

Data regarding access to diabetic neuropathy (DN) and diabetic foot (DF) examination, as well as the prevalence of these conditions in refugees and migrants (R&M) with diabetes mellitus (DM) residing in European countries are currently lacking. The study's primary objective was the estimation of DN and DF prevalence among diabetic R&M residing in Greece. Associations between DN diagnosis, demographic characteristics, glycemic control (HbA1c value), housing status and level of access to the National Healthcare System (ESY) were secondarily explored.

MATERIALS AND METHODS

R&M with DM were screened for DN/DF at the Doctors of the World's central polyclinic in Athens. For DN diagnosis, calculation of the Neuropathy Disability and Neuropathy Symptoms scores for each patient was followed by examination with 10 g Semmes-Weinstein monofilament. Demographic characteristics were also collected. Logistic regression was used for DN correlation with various variables. For HbA1c value association with the variables "Social Security Number (AMKA) possession" (representing access to ESY) and "unstable housing", Shapiro-Wilk regularity and Mann-Whitney tests were used. < 0.05 was selected as the cutoff for statistical significance.

RESULTS

From 67 patients examined, 47.8 % ( = 32) and 7.5 % ( = 5) were diagnosed with DN and DF respectively, while none had been previously screened for DN in Greece. In the single-factor analysis, age, years of diabetes and AMKA were significantly associated with DN. In the multivariate analysis, only age remained statistically significant. A statistically significant decrease in HbA1c values was observed in AMKA holders. Lower HbA1c values were observed in those with stable housing, but the association was not statistically significant.

CONCLUSION

A significant percentage of our study participants were diagnosed with DN and DF. Significantly lower HbA1c values were observed in patients with AMKA, thus underlining the importance of improving access to healthcare services for marginalized populations in Greece.

摘要

引言

目前缺乏关于欧洲国家糖尿病患者获得糖尿病神经病变(DN)和糖尿病足(DF)检查的相关数据,以及难民和移民(R&M)中这些病症的患病率数据。该研究的主要目的是估算居住在希腊的糖尿病难民和移民中DN和DF的患病率。其次,探讨DN诊断、人口统计学特征、血糖控制(糖化血红蛋白值)、住房状况与获得国家医疗保健系统(ESY)的机会之间的关联。

材料与方法

在雅典世界医生中心综合诊所对患有糖尿病的难民和移民进行DN/DF筛查。对于DN诊断,先计算每位患者的神经病变残疾和神经病变症状评分,然后用10克Semmes-Weinstein单丝进行检查。还收集了人口统计学特征。采用逻辑回归分析DN与各种变量的相关性。对于糖化血红蛋白值与“拥有社会保险号码(AMKA)”(代表获得ESY的机会)和“不稳定住房”变量的关联,使用了夏皮罗-威尔克正态性检验和曼-惠特尼检验。选择<0.05作为统计学显著性的临界值。

结果

在接受检查的67名患者中,分别有47.8%(=32)和7.5%(=5)被诊断为DN和DF,而此前在希腊没有人接受过DN筛查。在单因素分析中,年龄、糖尿病病程和AMKA与DN显著相关。在多因素分析中,只有年龄仍具有统计学显著性。持有AMKA者的糖化血红蛋白值有统计学显著性下降。住房稳定者的糖化血红蛋白值较低,但该关联无统计学显著性。

结论

我们研究中的很大一部分参与者被诊断为DN和DF。持有AMKA的患者糖化血红蛋白值显著较低,从而凸显了改善希腊边缘化人群获得医疗服务机会的重要性。

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