Levecke Madison, DeSisto Carla L, Womack Lindsay S, Okoroh Ekwutosi M, Cox Shanna, Kroelinger Charlan D, Barfield Wanda D
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America.
PLoS One. 2025 Aug 12;20(8):e0328916. doi: 10.1371/journal.pone.0328916. eCollection 2025.
The objective of this analysis is to examine characteristics of very preterm (VPT), very low birth weight (VLBW) infants not admitted to neonatal intensive care units (NICU). In this cross-sectional study assessing VPT (<32 weeks gestation) and VLBW (<1500 grams) infants, we used birth records from the National Vital Statistics System, 2021. Crude and adjusted prevalence ratios (aPR) with modified Poisson regression models were used to calculate prevalence of infants not admitted to the NICU by selected characteristics. Among 38,693 VPT, VLBW infants, 10% were not admitted to the NICU. In the adjusted model, characteristics associated with a higher prevalence of not being admitted to the NICU compared with analytical reference groups included non-Hispanic Native Hawaiian/Other Pacific Islander (aPR = 1.61;95% confidence interval [CI]:1.13-2.29), gestational age 22-24 weeks (aPR = 1.17;CI:1.08-1.26), vaginal delivery (aPR = 1.83;CI:1.73-1.94), and 5-minute Apgar score of 0-3 (aPR = 3.48;CI:3.18-3.82). Exploration of reasons infants were not admitted to the NICU may elucidate strategies to address barriers.
本分析的目的是研究未入住新生儿重症监护病房(NICU)的极早产儿(VPT)和极低出生体重儿(VLBW)的特征。在这项评估VPT(妊娠<32周)和VLBW(出生体重<1500克)婴儿的横断面研究中,我们使用了2021年国家生命统计系统的出生记录。采用修正泊松回归模型计算粗患病率和调整患病率比(aPR),以根据选定特征计算未入住NICU的婴儿患病率。在38693例VPT、VLBW婴儿中,10%未入住NICU。在调整模型中,与分析参考组相比,未入住NICU患病率较高的相关特征包括非西班牙裔夏威夷原住民/其他太平洋岛民(aPR = 1.61;95%置信区间[CI]:1.13 - 2.29)、孕龄22 - 24周(aPR = 1.17;CI:1.08 - 1.26)、阴道分娩(aPR = 1.83;CI:1.73 - 1.94)以及5分钟阿氏评分0 - 3分(aPR = 3.48;CI:3.18 - 3.82)。探究婴儿未入住NICU的原因可能会阐明解决障碍的策略。